Desmoplasia measured by computer assisted image analysis: an independent prognostic marker in colorectal carcinoma

Aims: The assessment of desmoplasia by traditional semiquantitative methods does not provide reliable prognostic data. The aim of this study was to quantify desmoplasia by computerised image analysis in primary colorectal carcinomas and to investigate its ability to predict overall survival. Methods...

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Veröffentlicht in:	Journal of clinical pathology 2005-01, Vol.58 (1), p.32-38
Hauptverfasser:	Sis, B, Sarioglu, S, Sokmen, S, Sakar, M, Kupelioglu, A, Fuzun, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Adenocarcinoma - secondary Adult Aged Aged, 80 and over Angiogenesis Apoptosis Blood Vessels - pathology coefficient of variation Collagen Colorectal cancer colorectal carcinoma Colorectal Neoplasms - pathology desmoplasia Extracellular matrix Fibrosis Follow-Up Studies Humans image analysis Image Processing, Computer-Assisted - methods Lymphatic system Lymphatic Vessels - pathology Medical prognosis Metastasis Methods Middle Aged Multivariate analysis Neoplasm Invasiveness Neoplasm Staging Original percentage of desmoplasia Prognosis Prostate cancer quantitative histochemistry Reproducibility of Results Rodents Studies Survival Analysis Tumors
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