Analysis of cell cycle regulator proteins in non-small cell lung cancer

Background/Aims: Abnormalities of the proteins involved in cell cycle checkpoints are extremely common among almost all neoplasms. This study aimed to investigate the expression of four components of the cell cycle machinery—p21, p16, p53, and proliferating cell nuclear antigen (PCNA)—in non-small c...

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Veröffentlicht in:	Journal of clinical pathology 2004-01, Vol.57 (1), p.58-63
Hauptverfasser:	Esposito, V, Baldi, A, Tonini, G, Vincenzi, B, Santini, M, Ambrogi, V, Mineo, T C, Persichetti, P, Liuzzi, G, Montesarchio, V, Wolner, E, Baldi, F, Groeger, A M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over ALND Analysis of Variance Antigens axillary lymph node dissection Biological and medical sciences Biomarkers, Tumor - metabolism Cancer therapies Carcinoma, Non-Small-Cell Lung - metabolism Carcinoma, Non-Small-Cell Lung - pathology Cell cycle Cell Cycle Proteins - metabolism Cell growth Cooperation Cyclin-Dependent Kinase Inhibitor p16 - metabolism Cyclin-Dependent Kinase Inhibitor p21 Cyclins - metabolism Deoxyribonucleic acid DNA Female Genes H&E haematoxylin and eosin Humans Hypotheses Immunoenzyme Techniques Immunoglobulins Investigative techniques, diagnostic techniques (general aspects) Kinases Lung cancer Lung Neoplasms - metabolism Lung Neoplasms - pathology LVI lymphovascular invasion Male Medical prognosis Medical sciences Middle Aged Multivariate analysis Neoplasm Proteins - metabolism Original Pathogenesis Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Pneumology Prognosis Proportional Hazards Models Proteins Regulation Retrospective Studies sentinel lymph node SLN Statistical analysis Studies Survival Analysis Thoracic surgery Tumor Suppressor Protein p53 - metabolism Tumors Tumors of the respiratory system and mediastinum
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