The value of haemostatic markers in the triage of patients with chest pain presenting with a normal or non-diagnostic ECG

The limited extent of coagulation activation in patients with cTnT positive ACS was reflected by the poor diagnostic performance of the haemostatic markers to identify these patients. Since these patients can be identified after serial measurement of cardiac serum markers, it remains a difficult tas...

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Veröffentlicht in:Heart (British Cardiac Society) 2005-09, Vol.91 (9), p.1215-1216
Hauptverfasser: Moons, A H M, van der Zee, P M, Bholasingh, R, Sturk, A, Hack, C E, Meijers, J C M, Kamp, O, Cornel, J H, Peters, R J G, de Winter, R J
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Sprache:eng
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Zusammenfassung:The limited extent of coagulation activation in patients with cTnT positive ACS was reflected by the poor diagnostic performance of the haemostatic markers to identify these patients. Since these patients can be identified after serial measurement of cardiac serum markers, it remains a difficult task to detect patients with an ACS without evidence of myocardial damage and presenting with a non-diagnostic ECG. On the basis of these markers, as many as 66-69% of the patients with cTnT negative ACS would still not have been detected. [...]in our study, which is limited by relatively small sample sizes, measurement of systemic plasma concentrations of haemostatic markers did not contribute to the triage of patients presenting with chest pain and a normal or non-diagnostic ECG to the emergency department.
ISSN:1355-6037
1468-201X
DOI:10.1136/hrt.2004.039644