Complement activation as a mediator of antiphospholipid antibody induced pregnancy loss and thrombosis

[...]current treatment regimens are imperfect and many treated pregnant patients suffer complications such as pre-eclampsia, uteroplacental insufficiency, intrauterine fetal growth restriction, and preterm birth. 11, 12 Thirdly, understanding how aPL antibodies "cause" miscarriage will pro...

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Veröffentlicht in:	Annals of the rheumatic diseases 2002-11, Vol.61 (suppl 2), p.ii46-50
Hauptverfasser:	Salmon, J E, Girardi, G, Holers, V M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Habitual - immunology Animals Antigens antiphoshpolipid antibody syndrome antiphospholipid antiphospholipid antibody syndrome Antiphospholipid Syndrome - immunology aPL APS Biological and medical sciences complement activation Complement Activation - immunology Complement C3 - immunology Female Humans Hypoxia Immune Tolerance Immunoglobulins Medical sciences Mice Miscarriage Pathogens Placenta Pregnancy Pregnancy Complications, Cardiovascular - immunology Rodents Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis SLE systemic lupus erythematosus Thrombosis Thrombosis - immunology
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