Empyema in a patient treated with infliximab: it is not what it seems

Reduced IgG levels can be the result of long term prednisone treatment or chronic infection. 1 Isolated IgG2 subclass deficiency may result in enhanced susceptibility to encapsulated bacteria. 2 Another report suggests an increased susceptibility to invasive pneumococcal disease in homozygotes for M...

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Veröffentlicht in:Annals of the rheumatic diseases 2005-11, Vol.64 (11), p.1657-1658
Hauptverfasser: Bossink, A, Thijsen, S, van Houte, A J
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container_issue 11
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container_title Annals of the rheumatic diseases
container_volume 64
creator Bossink, A
Thijsen, S
van Houte, A J
description Reduced IgG levels can be the result of long term prednisone treatment or chronic infection. 1 Isolated IgG2 subclass deficiency may result in enhanced susceptibility to encapsulated bacteria. 2 Another report suggests an increased susceptibility to invasive pneumococcal disease in homozygotes for MBL codon variants. 3 It is tempting to speculate that the immunomodulating effect of infliximab contributed to the two episodes of thoracic empyema.
doi_str_mv 10.1136/ard.2004.034959
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subjects Aged
Antibodies, Monoclonal - adverse effects
Antirheumatic Agents - adverse effects
Bacteria
empyema
Empyema, Pleural - etiology
Female
Humans
IgG Deficiency - complications
Infections
Infliximab
Letter
Opportunistic Infections - etiology
Pneumonia
title Empyema in a patient treated with infliximab: it is not what it seems
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