MMP profile in paired serum and synovial fluid samples of patients with rheumatoid arthritis

Objective: To analyse matrix metalloproteinases (MMPs) and tissue inhibitor-1 of MMPs (TIMP-1) levels in the systemic circulation and synovial fluid (SF) of patients with RA and to compare these levels with inflammatory and collagen degradation markers. Methods: ProMMP-1, -2, -3, -8, -9, TIMP-1, lev...

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Veröffentlicht in:	Annals of the rheumatic diseases 2004-07, Vol.63 (7), p.881-883
Hauptverfasser:	Tchetverikov, I, Ronday, H K, van El, B, Kiers, G H, Verzijl, N, TeKoppele, J M, Huizinga, T W J, DeGroot, J, Hanemaaijer, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged alpha-Macroglobulins - analysis Arthritis, Rheumatoid - enzymology Biological and medical sciences C reactive protein cartilage Case-Control Studies Collagen Collagenases - blood Concise Report CRP Disease Diseases of the osteoarticular system Enzyme Precursors - blood Enzyme-Linked Immunosorbent Assay - methods Enzymes Female Humans hydroxyproline Hydroxyproline - analysis Hypotheses Inflammation Inflammatory joint diseases Male Matrix Metalloproteinase 8 - analysis Matrix Metalloproteinase 8 - blood Matrix Metalloproteinase 9 - analysis Matrix Metalloproteinase 9 - blood matrix metalloproteinases Matrix Metalloproteinases - analysis Matrix Metalloproteinases - blood Medical sciences Metalloendopeptidases - blood Middle Aged MMPs OHPro osteoarthritis Osteoarthritis, Knee - enzymology Rheumatism Rheumatoid arthritis Statistics, Nonparametric Studies synovial fluid Synovial Fluid - enzymology TIMP Tissue Inhibitor of Metalloproteinase-1 - analysis Tissue Inhibitor of Metalloproteinase-1 - blood tissue inhibitors of metalloproteinases α2-macroglobulin α2M
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