HLA-DR-DQ haplotypes and genotypes in Finnish patients with rheumatoid arthritis

Objectives: To elucidate the contribution of HLA-DR-DQ haplotypes and their genotypic combinations to susceptibility to rheumatoid arthritis, and to evaluate the various models for HLA associated risk for the disease in a series of Finnish patients. Methods: 322 Finnish patients with rheumatoid arth...

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Veröffentlicht in:	Annals of the rheumatic diseases 2004-11, Vol.63 (11), p.1406-1412
Hauptverfasser:	Laivoranta-Nyman, S, Möttönen, T, Hermann, R, Tuokko, J, Luukkainen, R, Hakala, M, Hannonen, P, Korpela, M, Yli-Kerttula, U, Toivanen, A, Ilonen, J
Format:	Artikel
Sprache:	eng
Schlagworte:	AFBAC affected family based artificial controls Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - immunology Biological and medical sciences Case-Control Studies Chi-Square Distribution Diabetes Diseases of the osteoarticular system Extended Report Female Finland Gene Frequency Genes, MHC Class II Genetic Predisposition to Disease genetics Genotype Haplotypes HLA HLA-DQ Antigens - genetics HLA-DR Antigens - genetics human leucocyte A Humans HVR hypervariable region Hypotheses Inflammatory joint diseases major histocompatibility complex Male Medical sciences MHC Models, Genetic RAP Rheumatism Rheumatoid arthritis rheumatoid arthritis protection rheumatoid factor Risk Studies
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