Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: semiquantitative and quantitative analysis

Objectives: To compare receptor activator of NF-κB ligand (RANKL) production in the synovial tissue from patients with active rheumatoid arthritis (RA), inactive RA, spondyloarthropathies (SpA), osteoarthritis, and from normal subjects. In addition, to establish the cell lineages expressing RANKL in...

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Veröffentlicht in:	Annals of the rheumatic diseases 2002-12, Vol.61 (12), p.1047-1054
Hauptverfasser:	Crotti, T N, Smith, M D, Weedon, H, Ahern, M J, Findlay, D M, Kraan, M, Tak, P P, Haynes, D R
Format:	Artikel
Sprache:	eng
Schlagworte:	3-amino-9-ethylcarbazole AEC Biological and medical sciences bone DIA digital image analysis Diseases of the osteoarticular system Extended Report fibroblast-like synoviocytes FLS horseradish peroxidase HRP immunohistochemistry Inflammatory joint diseases integrated optical density interleukin IOD mAb mean optical density Medical sciences MOD monoclonal antibody OPG Osteoarthritis osteoprotegerin RANK RANKL receptor activator NF-κB ligand receptor activator of NF-κB receptor activator of NF-κB ligand rheumatoid arthritis semiquantitative assessment SpA spondyloarthropathies spondyloarthropathy SQA TNF tumour necrosis factor
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