Relevance of tumour necrosis factor‐α for the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw

1 The present study evaluated the participation of tumour necrosis factor‐α (TNF‐α) in the inflammatory and nociceptive responses evoked by carrageenan in the mouse paw. 2 The intraplantar injection of carrageenan (300 μg paw−1) induced a marked and biphasic paw oedema formation (peaks at 6 and 72 h...

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Veröffentlicht in:	British journal of pharmacology 2006-07, Vol.148 (5), p.688-695
Hauptverfasser:	Rocha, Ana C C, Fernandes, Elizabeth S, Quintão, Nara L M, Campos, Maria M, Calixto, João B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carrageenan Carrageenan - pharmacology cell migration Edema - chemically induced Foot - physiology Foot Diseases - chemically induced Foot Injuries - chemically induced Inflammation - chemically induced Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout mouse paw nociception oedema Pain - chemically induced Pain Measurement - drug effects Peroxidase - metabolism Pharmacology. Drug treatments TNF‐α Tumor Necrosis Factor-alpha - metabolism Tumor Necrosis Factor-alpha - physiology
Online-Zugang:	Volltext
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