The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation

1 The metabotropic glutamate receptor 4 (mGluR4) is a Gαi‐coupled receptor that modulates glutamatergic neurotransmission. As mGluR4 expression and activation have been implicated in a number of pathological conditions and because the internalization and desensitization properties of this receptor a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of pharmacology 2006-06, Vol.148 (3), p.279-290
Hauptverfasser:	Mathiesen, Jesper Mosolff, Ramirez, M Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylyl Cyclases - metabolism Biological and medical sciences cAMP Cell Line chimeric G protein desensitization Endocytosis Enzyme Activation - drug effects Humans inositol phosphate internalization Medical sciences mGluR4 Pharmacology. Drug treatments PMA protein kinase C Protein Kinase C - metabolism Receptors, Metabotropic Glutamate - agonists Receptors, Metabotropic Glutamate - genetics Receptors, Metabotropic Glutamate - metabolism Signal Transduction Transfection Type C Phospholipases - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!