Respiratory symptoms in older people and their association with mortality
Background: A study was undertaken to assess the prevalence of reported respiratory symptoms in a population aged over 75 years and their association with mortality. Methods: A total of 14 458 people aged 75 years and over participating in a trial of health screening of older people in general pract...
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| Veröffentlicht in: | Thorax 2005-04, Vol.60 (4), p.331-334 |
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| creator | Hewitt, J Smeeth, L Bulpitt, C J Tulloch, A J Fletcher, A E |
| description | Background: A study was undertaken to assess the prevalence of reported respiratory symptoms in a population aged over 75 years and their association with mortality. Methods: A total of 14 458 people aged 75 years and over participating in a trial of health screening of older people in general practice answered questions on three respiratory symptoms: cough, sputum production, and wheeze. The association of symptoms with mortality was examined for all cause and respiratory causes of death taking account of potential confounders. Results: Coughing up phlegm in winter mornings had a prevalence of 27.0% (95% confidence interval (CI) 26.8 to 27.2). Those with this symptom had an adjusted hazard ratio for all cause mortality of 1.35 (95% CI 1.21 to 1.50), p |
| doi_str_mv | 10.1136/thx.2004.029579 |
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Methods: A total of 14 458 people aged 75 years and over participating in a trial of health screening of older people in general practice answered questions on three respiratory symptoms: cough, sputum production, and wheeze. The association of symptoms with mortality was examined for all cause and respiratory causes of death taking account of potential confounders. Results: Coughing up phlegm in winter mornings had a prevalence of 27.0% (95% confidence interval (CI) 26.8 to 27.2). Those with this symptom had an adjusted hazard ratio for all cause mortality of 1.35 (95% CI 1.21 to 1.50), p<0.001 and for respiratory specific mortality of 2.01 (95% CI 1.66 to 2.41), p<0.001. Phlegm at any time of the day in winter had a prevalence of 16.5% (95% CI 16.3 to 16.7) with hazard ratios for all cause and respiratory specific mortality of 1.28 (95% CI 1.15 to 1.42) and 2.28 (95% CI 1.92 to 2.70), p<0.001. Wheeze or whistling from the chest had a prevalence of 14.3% (95% CI 14.1 to 14.5) with hazard ratios of 1.45 (95% CI 1.31 to 1.61) and 2.86 (95% CI 2.45 to 3.35), p<0.001. Conclusions: The prevalence of respiratory symptoms is widespread among elderly people and their presence is a strong predictor of mortality.</description><identifier>ISSN: 0040-6376</identifier><identifier>EISSN: 1468-3296</identifier><identifier>DOI: 10.1136/thx.2004.029579</identifier><identifier>PMID: 15790990</identifier><identifier>CODEN: THORA7</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Thoracic Society</publisher><subject>Aged ; Aged, 80 and over ; Asthma ; Biological and medical sciences ; Confidence Intervals ; Emphysema ; Epidemiology ; Female ; geriatrics ; Humans ; Male ; Medical sciences ; Mortality ; Older people ; Pneumology ; Prevalence ; Proportional Hazards Models ; Questionnaires ; Respiration Disorders - mortality ; Respiratory diseases ; respiratory symptoms ; Risk Factors ; Seasons ; Socioeconomic factors ; United Kingdom - epidemiology</subject><ispartof>Thorax, 2005-04, Vol.60 (4), p.331-334</ispartof><rights>Copyright 2005 Thorax</rights><rights>2005 INIST-CNRS</rights><rights>Copyright: 2005 Copyright 2005 Thorax</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b522t-d4da0beb906474773a5444b2a3de53a2e27b843ab2e5098adab1b25a84875fbd3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1747384/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1747384/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16739828$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15790990$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hewitt, J</creatorcontrib><creatorcontrib>Smeeth, L</creatorcontrib><creatorcontrib>Bulpitt, C J</creatorcontrib><creatorcontrib>Tulloch, A J</creatorcontrib><creatorcontrib>Fletcher, A E</creatorcontrib><title>Respiratory symptoms in older people and their association with mortality</title><title>Thorax</title><addtitle>Thorax</addtitle><description>Background: A study was undertaken to assess the prevalence of reported respiratory symptoms in a population aged over 75 years and their association with mortality. Methods: A total of 14 458 people aged 75 years and over participating in a trial of health screening of older people in general practice answered questions on three respiratory symptoms: cough, sputum production, and wheeze. The association of symptoms with mortality was examined for all cause and respiratory causes of death taking account of potential confounders. Results: Coughing up phlegm in winter mornings had a prevalence of 27.0% (95% confidence interval (CI) 26.8 to 27.2). Those with this symptom had an adjusted hazard ratio for all cause mortality of 1.35 (95% CI 1.21 to 1.50), p<0.001 and for respiratory specific mortality of 2.01 (95% CI 1.66 to 2.41), p<0.001. Phlegm at any time of the day in winter had a prevalence of 16.5% (95% CI 16.3 to 16.7) with hazard ratios for all cause and respiratory specific mortality of 1.28 (95% CI 1.15 to 1.42) and 2.28 (95% CI 1.92 to 2.70), p<0.001. Wheeze or whistling from the chest had a prevalence of 14.3% (95% CI 14.1 to 14.5) with hazard ratios of 1.45 (95% CI 1.31 to 1.61) and 2.86 (95% CI 2.45 to 3.35), p<0.001. Conclusions: The prevalence of respiratory symptoms is widespread among elderly people and their presence is a strong predictor of mortality.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Asthma</subject><subject>Biological and medical sciences</subject><subject>Confidence Intervals</subject><subject>Emphysema</subject><subject>Epidemiology</subject><subject>Female</subject><subject>geriatrics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Older people</subject><subject>Pneumology</subject><subject>Prevalence</subject><subject>Proportional Hazards Models</subject><subject>Questionnaires</subject><subject>Respiration Disorders - mortality</subject><subject>Respiratory diseases</subject><subject>respiratory symptoms</subject><subject>Risk Factors</subject><subject>Seasons</subject><subject>Socioeconomic factors</subject><subject>United Kingdom - epidemiology</subject><issn>0040-6376</issn><issn>1468-3296</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0UtvEzEUBWALgWgaWLNDIyG6QJrUb3s2lSDiUakqD_HaWdczDnGYGQ-2A82_x1WiFtiw8uJ-PvbVQegRwQtCmDzN66sFxZgvMG2Eau6gGeFS14w28i6alQGuJVPyCB2ntMEYa0LUfXREisVNg2fo_INLk4-QQ9xVaTdMOQyp8mMV-s7FanJh6l0FY1fltfOxgpRC6yH7MFa_fF5XQ4gZep93D9C9FfTJPTycc_Tp1cuPyzf1xdvX58vnF7UVlOa64x1g62yDJVdcKQaCc24psM4JBtRRZTVnYKkTuNHQgSWWCtBcK7GyHZujs33utLWD61o35gi9maIfIO5MAG_-nox-bb6Fn4aU51iJnqOTQ0AMP7YuZTP41Lq-h9GFbTJSCUExJQU--QduwjaOZbmSpYmSWOqmqNO9amNIKbrVzVcINtclmVKSuS7J7EsqNx7_ucGtP7RSwNMDgNRCv4owtj7dOqlYo6kurt47n7K7uplD_F6WYEqYy89Lo8X7y3cvvnw1tPhne2-HzX9_-RuVP7hc</recordid><startdate>20050401</startdate><enddate>20050401</enddate><creator>Hewitt, J</creator><creator>Smeeth, L</creator><creator>Bulpitt, C J</creator><creator>Tulloch, A J</creator><creator>Fletcher, A E</creator><general>BMJ Publishing Group Ltd and British Thoracic Society</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20050401</creationdate><title>Respiratory symptoms in older people and their association with mortality</title><author>Hewitt, J ; Smeeth, L ; Bulpitt, C J ; Tulloch, A J ; Fletcher, A E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b522t-d4da0beb906474773a5444b2a3de53a2e27b843ab2e5098adab1b25a84875fbd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Asthma</topic><topic>Biological and medical sciences</topic><topic>Confidence Intervals</topic><topic>Emphysema</topic><topic>Epidemiology</topic><topic>Female</topic><topic>geriatrics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mortality</topic><topic>Older people</topic><topic>Pneumology</topic><topic>Prevalence</topic><topic>Proportional Hazards Models</topic><topic>Questionnaires</topic><topic>Respiration Disorders - mortality</topic><topic>Respiratory diseases</topic><topic>respiratory symptoms</topic><topic>Risk Factors</topic><topic>Seasons</topic><topic>Socioeconomic factors</topic><topic>United Kingdom - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hewitt, J</creatorcontrib><creatorcontrib>Smeeth, L</creatorcontrib><creatorcontrib>Bulpitt, C J</creatorcontrib><creatorcontrib>Tulloch, A J</creatorcontrib><creatorcontrib>Fletcher, A E</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Thorax</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hewitt, J</au><au>Smeeth, L</au><au>Bulpitt, C J</au><au>Tulloch, A J</au><au>Fletcher, A E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Respiratory symptoms in older people and their association with mortality</atitle><jtitle>Thorax</jtitle><addtitle>Thorax</addtitle><date>2005-04-01</date><risdate>2005</risdate><volume>60</volume><issue>4</issue><spage>331</spage><epage>334</epage><pages>331-334</pages><issn>0040-6376</issn><eissn>1468-3296</eissn><coden>THORA7</coden><abstract>Background: A study was undertaken to assess the prevalence of reported respiratory symptoms in a population aged over 75 years and their association with mortality. Methods: A total of 14 458 people aged 75 years and over participating in a trial of health screening of older people in general practice answered questions on three respiratory symptoms: cough, sputum production, and wheeze. The association of symptoms with mortality was examined for all cause and respiratory causes of death taking account of potential confounders. Results: Coughing up phlegm in winter mornings had a prevalence of 27.0% (95% confidence interval (CI) 26.8 to 27.2). Those with this symptom had an adjusted hazard ratio for all cause mortality of 1.35 (95% CI 1.21 to 1.50), p<0.001 and for respiratory specific mortality of 2.01 (95% CI 1.66 to 2.41), p<0.001. Phlegm at any time of the day in winter had a prevalence of 16.5% (95% CI 16.3 to 16.7) with hazard ratios for all cause and respiratory specific mortality of 1.28 (95% CI 1.15 to 1.42) and 2.28 (95% CI 1.92 to 2.70), p<0.001. Wheeze or whistling from the chest had a prevalence of 14.3% (95% CI 14.1 to 14.5) with hazard ratios of 1.45 (95% CI 1.31 to 1.61) and 2.86 (95% CI 2.45 to 3.35), p<0.001. Conclusions: The prevalence of respiratory symptoms is widespread among elderly people and their presence is a strong predictor of mortality.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Thoracic Society</pub><pmid>15790990</pmid><doi>10.1136/thx.2004.029579</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aged Aged, 80 and over Asthma Biological and medical sciences Confidence Intervals Emphysema Epidemiology Female geriatrics Humans Male Medical sciences Mortality Older people Pneumology Prevalence Proportional Hazards Models Questionnaires Respiration Disorders - mortality Respiratory diseases respiratory symptoms Risk Factors Seasons Socioeconomic factors United Kingdom - epidemiology |
| title | Respiratory symptoms in older people and their association with mortality |
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