α1-Antitrypsin deficiency • 3: Clinical manifestations and natural history
A review of the clinical manifestations of α1-antitrypsin (AAT) deficiency, including lung disease and liver disease, and risk factors affecting the rate of decline in lung function in AAT deficient patients.
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Veröffentlicht in: | Thorax 2004-05, Vol.59 (5), p.441-445 |
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creator | Needham, M Stockley, R A |
description | A review of the clinical manifestations of α1-antitrypsin (AAT) deficiency, including lung disease and liver disease, and risk factors affecting the rate of decline in lung function in AAT deficient patients. |
doi_str_mv | 10.1136/thx.2003.006510 |
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Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>liver disease</subject><subject>lung function</subject><subject>Medical sciences</subject><subject>Pneumology</subject><subject>Review Series</subject><subject>smoking</subject><subject>α1-antitrypsin deficiency</subject><issn>0040-6376</issn><issn>1468-3296</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNpVkU1OwzAQhS0EglJYs82GDVKKJxM7KQskVPEnFdjwt7MmiU0NrVvFBtEdZ-EGXIRDcBJcFYHYzIz0nj7N02NsB3gPAOV-GL32Ms6xx7kUwFdYB3JZppj15SrrcJ7zVGIhN9im94-c8xKgWGcbIABEWZQddvH5AemRCza085m3Lmm0sbXVrp4nX2_vCR4kg7F1tqZxMiFnjfaBgp06n5BrEkfhuY3SyPowbedbbM3Q2Ovtn91lNyfH14OzdHh1ej44GqZVlsmQCtKY1XForChHHW8jqEQkJKqgryvJqUKjAXQuTC5Fo8sCZGN0RgYRu-xwyZ09VxPd1NqF-IWatXZC7VxNyar_irMj9TB9UVDksl-KCNj9AZCP0UxLrrb-FwCiiN_08-hLl76YT7_-6tQ-KVlgIdTl7UDdnd7D8ASu1W307y391eTxj8bVoiwVy1KLstSyLPwGNoqJRA</recordid><startdate>200405</startdate><enddate>200405</enddate><creator>Needham, M</creator><creator>Stockley, R A</creator><general>BMJ Publishing Group Ltd and British Thoracic Society</general><general>BMJ</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>5PM</scope></search><sort><creationdate>200405</creationdate><title>α1-Antitrypsin deficiency • 3: Clinical manifestations and natural history</title><author>Needham, M ; Stockley, R A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b226t-5ae32cae3e3ba43e2caf5a833a3aab19eb60ab3fe11e45f465de8716dfe2af333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cardiology. Vascular system</topic><topic>liver disease</topic><topic>lung function</topic><topic>Medical sciences</topic><topic>Pneumology</topic><topic>Review Series</topic><topic>smoking</topic><topic>α1-antitrypsin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Needham, M</creatorcontrib><creatorcontrib>Stockley, R A</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Thorax</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Needham, M</au><au>Stockley, R A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>α1-Antitrypsin deficiency • 3: Clinical manifestations and natural history</atitle><jtitle>Thorax</jtitle><addtitle>Thorax</addtitle><date>2004-05</date><risdate>2004</risdate><volume>59</volume><issue>5</issue><spage>441</spage><epage>445</epage><pages>441-445</pages><issn>0040-6376</issn><eissn>1468-3296</eissn><coden>THORA7</coden><abstract>A review of the clinical manifestations of α1-antitrypsin (AAT) deficiency, including lung disease and liver disease, and risk factors affecting the rate of decline in lung function in AAT deficient patients.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Thoracic Society</pub><pmid>15115878</pmid><doi>10.1136/thx.2003.006510</doi><tpages>5</tpages></addata></record> |
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subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiology. Vascular system liver disease lung function Medical sciences Pneumology Review Series smoking α1-antitrypsin deficiency |
title | α1-Antitrypsin deficiency • 3: Clinical manifestations and natural history |
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