Expression of protease activated receptor-2 (PAR-2) in central airways of smokers and non-smokers

Background: Protease activated receptor-2 (PAR-2) is a transmembrane G protein coupled receptor preferentially activated by trypsin and tryptase. The protease activated receptors play an important role in most components of injury responses including cell proliferation, migration, matrix remodelling...

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Veröffentlicht in:	Thorax 2002-02, Vol.57 (2), p.146-151
Hauptverfasser:	Miotto, D, Hollenberg, M D, Bunnett, N W, Papi, A, Braccioni, F, Boschetto, P, Rea, F, Zuin, A, Geppetti, P, Saetta, M, Maestrelli, P, Fabbri, L M, Mapp, C E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Airway management Allergens Antibodies Asymptomatic Biological and medical sciences Bronchi - metabolism Bronchitis Chronic obstructive pulmonary disease Female Forced Expiratory Volume - physiology Humans Male Medical sciences Muscle, Smooth - metabolism Original Peptides Pulmonary arteries Receptor, PAR-2 Receptors, Thrombin - metabolism Respiratory Muscles - metabolism Smoking - metabolism Smoking - pathology Smoking - physiopathology Smooth muscle Surgery Tobacco, tobacco smoking Toxicology Vital Capacity - physiology
Online-Zugang:	Volltext
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