Acute hepatocellular and cholestatic injury in a patient taking celecoxib

A case of acute hepatocellular and cholestatic liver injury that may have been associated with the use of celecoxib is described. This case was reported to US Food and Drug Administration and the manufacturer of celecoxib.

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Bibliographische Detailangaben
Veröffentlicht in:	Postgraduate medical journal 2001-08, Vol.77 (910), p.548-550
Hauptverfasser:	Nachimuthu, S, Volfinzon, L, Gopal, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen acute hepatic injury Adverse Drug Reaction of the Month adverse effects Aged Anti-Inflammatory Agents, Non-Steroidal - adverse effects Arthritis Biological and medical sciences Celecoxib Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - physiopathology Cholestasis - chemically induced Cholestasis - physiopathology Complications and side effects COX-2 inhibitors Cyclooxygenase Inhibitors - adverse effects Dehydrogenases Drug toxicity and drugs side effects treatment Female Hepatitis Humans Injuries Liver Liver Function Tests Medical sciences Osteoarthritis Osteoarthritis - drug therapy Patients Pharmacology. Drug treatments Phosphatase Pyrazoles Sulfonamides - adverse effects Toxicity: digestive system
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Beschreibung
Zusammenfassung:	A case of acute hepatocellular and cholestatic liver injury that may have been associated with the use of celecoxib is described. This case was reported to US Food and Drug Administration and the manufacturer of celecoxib.
ISSN:	0032-5473 1469-0756
DOI:	10.1136/pmj.77.910.548