Increased nitric oxide in exhaled air: an early marker of asthma in non-smoking aluminium potroom workers?
OBJECTIVES To study exhaled nitric oxide (NO) as a marker of airway inflammation caused by potroom exposure, hypothesising that (a) workers exposed to potroom pollutants would have higher concentrations of NO in expired air than control subjects employed at the same plant but working outside of the...
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| Veröffentlicht in: | Occupational and environmental medicine (London, England) England), 2000-04, Vol.57 (4), p.274-278 |
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| creator | Lund, M B Øksne, P I Hamre, R Kongerud, J |
| description | OBJECTIVES To study exhaled nitric oxide (NO) as a marker of airway inflammation caused by potroom exposure, hypothesising that (a) workers exposed to potroom pollutants would have higher concentrations of NO in expired air than control subjects employed at the same plant but working outside of the potroom atmosphere, and (b) that concentrations of exhaled NO in potroom employees might be positively associated with concentrations of fluoride and exposure to dust. METHODS A study group comprising 186 male subjects (aged 24–63 years), employed in the potrooms of one Norwegian aluminium smelter, and 40 comparable control subjects (aged 25–60 years) recruited from the same plant, were examined by measurements of exhaled and nasal concentrations of NO, spirometry, and a questionnaire on respiratory symptoms as a part of an annual health surveillance programme. Estimates of exposure to fluorides and dust for selected job categories were obtained by means of personal samplers carried by the workers. RESULTS In the non-smokers, the concentrations of exhaled NO were higher in the potroom workers than in the controls (median (interquartile range) 9.3 (6.2–15.6) v 5.7 (4.6–8.3) ppb, p=0.001). The two groups did not differ in spirometry and asthma-like symptoms. Non-smoking potroom workers with asthma-like symptoms had higher concentrations of exhaled NO than those with no symptoms (median (interquartile range) 21.0 (19.3–41.4)v 8.5 (5.9–12.8) ppb, p=0.001), but had comparable spirometric values. In subjects who smoked, the concentrations of exhaled NO did not differ significantly between potroom workers and controls (median (interquartile range) 4.6 (3.3–8.0) v 4.0 (3.4–5.1) ppb. Exhaled NO was not significantly associated with either duration of employment or routine measurements of dust and fluorides. CONCLUSIONS Exposure to potroom pollutants is associated with increased concentrations of exhaled NO in non-smoking subjects. Nitric oxide in exhaled air may be an early marker of airway inflammation in aluminium potroom workers. |
| doi_str_mv | 10.1136/oem.57.4.274 |
| format | Article |
| fullrecord | <record><control><sourceid>jstor_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739946</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>27731300</jstor_id><sourcerecordid>27731300</sourcerecordid><originalsourceid>FETCH-LOGICAL-b561t-6a3b9065a77c385c4ed6ee5d7517ffbb47f8d0544d6172b0eea0605b8f6c63d83</originalsourceid><addsrcrecordid>eNp9kUtv1DAUhSMEoqWwYwuyRCU2ZPCNHzdhQYVGUFpGsOGxtJzE6Xia2IOdwPTf49GMpoUFKz_O56NzfbLsKdAZAJOvvRlmAmd8ViC_lx0DR5pjVcj7ac8E5BQBjrJHMa4oBYaseJgdAS2BAojjbHXhmmB0NC1xdgy2IX5jW0OsI2az1H261za8ITqddehvyKDDtQnEd0THcTnoLem8y-Pgr627IrqfBuvsNJC1H4P3A_ntty_i2ePsQaf7aJ7s15Ps24f3X-cf88WX84v5u0VeCwljLjWrKyqFRmxYKRpuWmmMaFEAdl1dc-zKlgrOWwlY1NQYTSUVddnJRrK2ZCfZ253veqoH0zbGjUH3ah1syn6jvLbqb8XZpbryvxQgqyouk8HLvUHwPycTRzXY2Ji-1874KSrkjAEKBol88Q-58lNwabpkVoIQUEqWqFc7qgk-xmC6QxagatuhSh0qgYqr1GHCn9_NfwfelZaA0z2gY6P7LmjX2HjLFRVKtsWe7bBVHH04yAViSk5p0vOdbuNoNgc99askMhTq8_e5-iEvP10uKq7Ob7-lHlb_n-APC2DLCA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1781551863</pqid></control><display><type>article</type><title>Increased nitric oxide in exhaled air: an early marker of asthma in non-smoking aluminium potroom workers?</title><source>Jstor Complete Legacy</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Lund, M B ; Øksne, P I ; Hamre, R ; Kongerud, J</creator><creatorcontrib>Lund, M B ; Øksne, P I ; Hamre, R ; Kongerud, J</creatorcontrib><description>OBJECTIVES To study exhaled nitric oxide (NO) as a marker of airway inflammation caused by potroom exposure, hypothesising that (a) workers exposed to potroom pollutants would have higher concentrations of NO in expired air than control subjects employed at the same plant but working outside of the potroom atmosphere, and (b) that concentrations of exhaled NO in potroom employees might be positively associated with concentrations of fluoride and exposure to dust. METHODS A study group comprising 186 male subjects (aged 24–63 years), employed in the potrooms of one Norwegian aluminium smelter, and 40 comparable control subjects (aged 25–60 years) recruited from the same plant, were examined by measurements of exhaled and nasal concentrations of NO, spirometry, and a questionnaire on respiratory symptoms as a part of an annual health surveillance programme. Estimates of exposure to fluorides and dust for selected job categories were obtained by means of personal samplers carried by the workers. RESULTS In the non-smokers, the concentrations of exhaled NO were higher in the potroom workers than in the controls (median (interquartile range) 9.3 (6.2–15.6) v 5.7 (4.6–8.3) ppb, p=0.001). The two groups did not differ in spirometry and asthma-like symptoms. Non-smoking potroom workers with asthma-like symptoms had higher concentrations of exhaled NO than those with no symptoms (median (interquartile range) 21.0 (19.3–41.4)v 8.5 (5.9–12.8) ppb, p=0.001), but had comparable spirometric values. In subjects who smoked, the concentrations of exhaled NO did not differ significantly between potroom workers and controls (median (interquartile range) 4.6 (3.3–8.0) v 4.0 (3.4–5.1) ppb. Exhaled NO was not significantly associated with either duration of employment or routine measurements of dust and fluorides. CONCLUSIONS Exposure to potroom pollutants is associated with increased concentrations of exhaled NO in non-smoking subjects. Nitric oxide in exhaled air may be an early marker of airway inflammation in aluminium potroom workers.</description><identifier>ISSN: 1351-0711</identifier><identifier>EISSN: 1470-7926</identifier><identifier>DOI: 10.1136/oem.57.4.274</identifier><identifier>PMID: 10810115</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Adult ; Air Pollutants, Occupational - adverse effects ; Aluminum ; Aluminum - adverse effects ; Asthma ; Asthma - diagnosis ; Biological and medical sciences ; Biomarkers - analysis ; Breath tests ; Chemical compounds (mineral, organic) ; Chemical, physic and infectious diseases ; Chronic obstructive pulmonary disease, asthma ; Cigarette smoking ; Control groups ; Dust ; Dyspnea ; Employment ; Fluorides ; Forced Expiratory Volume - physiology ; Humans ; Infections ; Inflammation ; Male ; Medical sciences ; Middle Aged ; Nitric oxide ; Nitric Oxide - analysis ; Norway - epidemiology ; occupational asthma ; Occupational Diseases - diagnosis ; Occupational exposure ; Occupational Exposure - adverse effects ; Occupational medicine ; Oxides ; Particulate matter ; Pneumology ; Pollutants ; potroom workers ; Public health. Hygiene-occupational medicine ; Questionnaires ; Research parks ; Respiratory Hypersensitivity - chemically induced ; Samplers ; Smelters ; Smoke ; Smoking ; Smoking - epidemiology ; Spirometry ; Vital capacity ; Vital Capacity - physiology</subject><ispartof>Occupational and environmental medicine (London, England), 2000-04, Vol.57 (4), p.274-278</ispartof><rights>Occupational and Environmental Medicine</rights><rights>2000 INIST-CNRS</rights><rights>Copyright: 2000 Occupational and Environmental Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b561t-6a3b9065a77c385c4ed6ee5d7517ffbb47f8d0544d6172b0eea0605b8f6c63d83</citedby><cites>FETCH-LOGICAL-b561t-6a3b9065a77c385c4ed6ee5d7517ffbb47f8d0544d6172b0eea0605b8f6c63d83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/27731300$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/27731300$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,723,776,780,799,881,27901,27902,53766,53768,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1297635$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10810115$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lund, M B</creatorcontrib><creatorcontrib>Øksne, P I</creatorcontrib><creatorcontrib>Hamre, R</creatorcontrib><creatorcontrib>Kongerud, J</creatorcontrib><title>Increased nitric oxide in exhaled air: an early marker of asthma in non-smoking aluminium potroom workers?</title><title>Occupational and environmental medicine (London, England)</title><addtitle>Occup Environ Med</addtitle><description>OBJECTIVES To study exhaled nitric oxide (NO) as a marker of airway inflammation caused by potroom exposure, hypothesising that (a) workers exposed to potroom pollutants would have higher concentrations of NO in expired air than control subjects employed at the same plant but working outside of the potroom atmosphere, and (b) that concentrations of exhaled NO in potroom employees might be positively associated with concentrations of fluoride and exposure to dust. METHODS A study group comprising 186 male subjects (aged 24–63 years), employed in the potrooms of one Norwegian aluminium smelter, and 40 comparable control subjects (aged 25–60 years) recruited from the same plant, were examined by measurements of exhaled and nasal concentrations of NO, spirometry, and a questionnaire on respiratory symptoms as a part of an annual health surveillance programme. Estimates of exposure to fluorides and dust for selected job categories were obtained by means of personal samplers carried by the workers. RESULTS In the non-smokers, the concentrations of exhaled NO were higher in the potroom workers than in the controls (median (interquartile range) 9.3 (6.2–15.6) v 5.7 (4.6–8.3) ppb, p=0.001). The two groups did not differ in spirometry and asthma-like symptoms. Non-smoking potroom workers with asthma-like symptoms had higher concentrations of exhaled NO than those with no symptoms (median (interquartile range) 21.0 (19.3–41.4)v 8.5 (5.9–12.8) ppb, p=0.001), but had comparable spirometric values. In subjects who smoked, the concentrations of exhaled NO did not differ significantly between potroom workers and controls (median (interquartile range) 4.6 (3.3–8.0) v 4.0 (3.4–5.1) ppb. Exhaled NO was not significantly associated with either duration of employment or routine measurements of dust and fluorides. CONCLUSIONS Exposure to potroom pollutants is associated with increased concentrations of exhaled NO in non-smoking subjects. Nitric oxide in exhaled air may be an early marker of airway inflammation in aluminium potroom workers.</description><subject>Adult</subject><subject>Air Pollutants, Occupational - adverse effects</subject><subject>Aluminum</subject><subject>Aluminum - adverse effects</subject><subject>Asthma</subject><subject>Asthma - diagnosis</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - analysis</subject><subject>Breath tests</subject><subject>Chemical compounds (mineral, organic)</subject><subject>Chemical, physic and infectious diseases</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Cigarette smoking</subject><subject>Control groups</subject><subject>Dust</subject><subject>Dyspnea</subject><subject>Employment</subject><subject>Fluorides</subject><subject>Forced Expiratory Volume - physiology</subject><subject>Humans</subject><subject>Infections</subject><subject>Inflammation</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nitric oxide</subject><subject>Nitric Oxide - analysis</subject><subject>Norway - epidemiology</subject><subject>occupational asthma</subject><subject>Occupational Diseases - diagnosis</subject><subject>Occupational exposure</subject><subject>Occupational Exposure - adverse effects</subject><subject>Occupational medicine</subject><subject>Oxides</subject><subject>Particulate matter</subject><subject>Pneumology</subject><subject>Pollutants</subject><subject>potroom workers</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Questionnaires</subject><subject>Research parks</subject><subject>Respiratory Hypersensitivity - chemically induced</subject><subject>Samplers</subject><subject>Smelters</subject><subject>Smoke</subject><subject>Smoking</subject><subject>Smoking - epidemiology</subject><subject>Spirometry</subject><subject>Vital capacity</subject><subject>Vital Capacity - physiology</subject><issn>1351-0711</issn><issn>1470-7926</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kUtv1DAUhSMEoqWwYwuyRCU2ZPCNHzdhQYVGUFpGsOGxtJzE6Xia2IOdwPTf49GMpoUFKz_O56NzfbLsKdAZAJOvvRlmAmd8ViC_lx0DR5pjVcj7ac8E5BQBjrJHMa4oBYaseJgdAS2BAojjbHXhmmB0NC1xdgy2IX5jW0OsI2az1H261za8ITqddehvyKDDtQnEd0THcTnoLem8y-Pgr627IrqfBuvsNJC1H4P3A_ntty_i2ePsQaf7aJ7s15Ps24f3X-cf88WX84v5u0VeCwljLjWrKyqFRmxYKRpuWmmMaFEAdl1dc-zKlgrOWwlY1NQYTSUVddnJRrK2ZCfZ253veqoH0zbGjUH3ah1syn6jvLbqb8XZpbryvxQgqyouk8HLvUHwPycTRzXY2Ji-1874KSrkjAEKBol88Q-58lNwabpkVoIQUEqWqFc7qgk-xmC6QxagatuhSh0qgYqr1GHCn9_NfwfelZaA0z2gY6P7LmjX2HjLFRVKtsWe7bBVHH04yAViSk5p0vOdbuNoNgc99askMhTq8_e5-iEvP10uKq7Ob7-lHlb_n-APC2DLCA</recordid><startdate>20000401</startdate><enddate>20000401</enddate><creator>Lund, M B</creator><creator>Øksne, P I</creator><creator>Hamre, R</creator><creator>Kongerud, J</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>L6V</scope><scope>M0S</scope><scope>M1P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>PATMY</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>7QQ</scope><scope>7TB</scope><scope>8FD</scope><scope>FR3</scope><scope>JG9</scope><scope>KR7</scope><scope>5PM</scope></search><sort><creationdate>20000401</creationdate><title>Increased nitric oxide in exhaled air: an early marker of asthma in non-smoking aluminium potroom workers?</title><author>Lund, M B ; Øksne, P I ; Hamre, R ; Kongerud, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b561t-6a3b9065a77c385c4ed6ee5d7517ffbb47f8d0544d6172b0eea0605b8f6c63d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Air Pollutants, Occupational - adverse effects</topic><topic>Aluminum</topic><topic>Aluminum - adverse effects</topic><topic>Asthma</topic><topic>Asthma - diagnosis</topic><topic>Biological and medical sciences</topic><topic>Biomarkers - analysis</topic><topic>Breath tests</topic><topic>Chemical compounds (mineral, organic)</topic><topic>Chemical, physic and infectious diseases</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Cigarette smoking</topic><topic>Control groups</topic><topic>Dust</topic><topic>Dyspnea</topic><topic>Employment</topic><topic>Fluorides</topic><topic>Forced Expiratory Volume - physiology</topic><topic>Humans</topic><topic>Infections</topic><topic>Inflammation</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nitric oxide</topic><topic>Nitric Oxide - analysis</topic><topic>Norway - epidemiology</topic><topic>occupational asthma</topic><topic>Occupational Diseases - diagnosis</topic><topic>Occupational exposure</topic><topic>Occupational Exposure - adverse effects</topic><topic>Occupational medicine</topic><topic>Oxides</topic><topic>Particulate matter</topic><topic>Pneumology</topic><topic>Pollutants</topic><topic>potroom workers</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Questionnaires</topic><topic>Research parks</topic><topic>Respiratory Hypersensitivity - chemically induced</topic><topic>Samplers</topic><topic>Smelters</topic><topic>Smoke</topic><topic>Smoking</topic><topic>Smoking - epidemiology</topic><topic>Spirometry</topic><topic>Vital capacity</topic><topic>Vital Capacity - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lund, M B</creatorcontrib><creatorcontrib>Øksne, P I</creatorcontrib><creatorcontrib>Hamre, R</creatorcontrib><creatorcontrib>Kongerud, J</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & 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England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lund, M B</au><au>Øksne, P I</au><au>Hamre, R</au><au>Kongerud, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased nitric oxide in exhaled air: an early marker of asthma in non-smoking aluminium potroom workers?</atitle><jtitle>Occupational and environmental medicine (London, England)</jtitle><addtitle>Occup Environ Med</addtitle><date>2000-04-01</date><risdate>2000</risdate><volume>57</volume><issue>4</issue><spage>274</spage><epage>278</epage><pages>274-278</pages><issn>1351-0711</issn><eissn>1470-7926</eissn><abstract>OBJECTIVES To study exhaled nitric oxide (NO) as a marker of airway inflammation caused by potroom exposure, hypothesising that (a) workers exposed to potroom pollutants would have higher concentrations of NO in expired air than control subjects employed at the same plant but working outside of the potroom atmosphere, and (b) that concentrations of exhaled NO in potroom employees might be positively associated with concentrations of fluoride and exposure to dust. METHODS A study group comprising 186 male subjects (aged 24–63 years), employed in the potrooms of one Norwegian aluminium smelter, and 40 comparable control subjects (aged 25–60 years) recruited from the same plant, were examined by measurements of exhaled and nasal concentrations of NO, spirometry, and a questionnaire on respiratory symptoms as a part of an annual health surveillance programme. Estimates of exposure to fluorides and dust for selected job categories were obtained by means of personal samplers carried by the workers. RESULTS In the non-smokers, the concentrations of exhaled NO were higher in the potroom workers than in the controls (median (interquartile range) 9.3 (6.2–15.6) v 5.7 (4.6–8.3) ppb, p=0.001). The two groups did not differ in spirometry and asthma-like symptoms. Non-smoking potroom workers with asthma-like symptoms had higher concentrations of exhaled NO than those with no symptoms (median (interquartile range) 21.0 (19.3–41.4)v 8.5 (5.9–12.8) ppb, p=0.001), but had comparable spirometric values. In subjects who smoked, the concentrations of exhaled NO did not differ significantly between potroom workers and controls (median (interquartile range) 4.6 (3.3–8.0) v 4.0 (3.4–5.1) ppb. Exhaled NO was not significantly associated with either duration of employment or routine measurements of dust and fluorides. CONCLUSIONS Exposure to potroom pollutants is associated with increased concentrations of exhaled NO in non-smoking subjects. Nitric oxide in exhaled air may be an early marker of airway inflammation in aluminium potroom workers.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>10810115</pmid><doi>10.1136/oem.57.4.274</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1351-0711 |
| ispartof | Occupational and environmental medicine (London, England), 2000-04, Vol.57 (4), p.274-278 |
| issn | 1351-0711 1470-7926 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1739946 |
| source | Jstor Complete Legacy; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Air Pollutants, Occupational - adverse effects Aluminum Aluminum - adverse effects Asthma Asthma - diagnosis Biological and medical sciences Biomarkers - analysis Breath tests Chemical compounds (mineral, organic) Chemical, physic and infectious diseases Chronic obstructive pulmonary disease, asthma Cigarette smoking Control groups Dust Dyspnea Employment Fluorides Forced Expiratory Volume - physiology Humans Infections Inflammation Male Medical sciences Middle Aged Nitric oxide Nitric Oxide - analysis Norway - epidemiology occupational asthma Occupational Diseases - diagnosis Occupational exposure Occupational Exposure - adverse effects Occupational medicine Oxides Particulate matter Pneumology Pollutants potroom workers Public health. Hygiene-occupational medicine Questionnaires Research parks Respiratory Hypersensitivity - chemically induced Samplers Smelters Smoke Smoking Smoking - epidemiology Spirometry Vital capacity Vital Capacity - physiology |
| title | Increased nitric oxide in exhaled air: an early marker of asthma in non-smoking aluminium potroom workers? |
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