Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study
Cognitive decline is commonly stated as one of the main risk factors for delirium. The aim was to assess the importance of a delirium episode as a symptom of an underlying dementia among community dwelling healthy elderly people in a prospective 2 year follow up study. The study patients consisted o...
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Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2000-10, Vol.69 (4), p.519-521 |
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creator | Rahkonen, Terhi Luukkainen-Markkula, Riitta Paanila, Satu Sivenius, Juhani Sulkava, Raimo |
description | Cognitive decline is commonly stated as one of the main risk factors for delirium. The aim was to assess the importance of a delirium episode as a symptom of an underlying dementia among community dwelling healthy elderly people in a prospective 2 year follow up study. The study patients consisted of 51 people living at home and older than 65 years of age, without severe underlying disorders including diagnosed dementia, admitted consecutively as emergency cases to hospital because of an acute delirious state and followed up for 2 years. The diagnosis of delirium and dementia were based on the DSM-III-R criteria. The community dwelling patients were evaluated and tested annually by a clinical investigator, a geriatric study nurse, and a neuropsychologist. The medical records of the institutionalised patients were also evaluated. Dementia was diagnosed immediately after the assurance that delirium symptoms had subsided in 14 out of 51 subjects (27%) and the additional 14 subjects were diagnosed as being demented during the 2 year follow up, 28 out of 51 patients (55%) altogether. Alzheimer's disease or mixed dementia was diagnosed in 14 out of 51 patients (27%), vascular dementia in 10 (20%), and dementia with Lewy bodies in two (4%). One case of alcoholic dementia and one case of a non-alcoholic hepatic encephalopathia were also found. A delirium episode is often the first sign of dementia requiring attention from medical and social professionals. |
doi_str_mv | 10.1136/jnnp.69.4.519 |
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The aim was to assess the importance of a delirium episode as a symptom of an underlying dementia among community dwelling healthy elderly people in a prospective 2 year follow up study. The study patients consisted of 51 people living at home and older than 65 years of age, without severe underlying disorders including diagnosed dementia, admitted consecutively as emergency cases to hospital because of an acute delirious state and followed up for 2 years. The diagnosis of delirium and dementia were based on the DSM-III-R criteria. The community dwelling patients were evaluated and tested annually by a clinical investigator, a geriatric study nurse, and a neuropsychologist. The medical records of the institutionalised patients were also evaluated. Dementia was diagnosed immediately after the assurance that delirium symptoms had subsided in 14 out of 51 subjects (27%) and the additional 14 subjects were diagnosed as being demented during the 2 year follow up, 28 out of 51 patients (55%) altogether. Alzheimer's disease or mixed dementia was diagnosed in 14 out of 51 patients (27%), vascular dementia in 10 (20%), and dementia with Lewy bodies in two (4%). One case of alcoholic dementia and one case of a non-alcoholic hepatic encephalopathia were also found. A delirium episode is often the first sign of dementia requiring attention from medical and social professionals.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.69.4.519</identifier><identifier>PMID: 10990515</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Aged ; Aged, 80 and over ; Aging - physiology ; Biological and medical sciences ; Brain research ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; delirium ; Delirium - physiopathology ; Dementia ; Dementia - diagnosis ; Dementia - physiopathology ; elderly ; Finland ; Follow-Up Studies ; Humans ; Male ; Medical sciences ; Mortality ; Neurology ; Neuropsychological Tests ; Older people ; Short Report ; Studies</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 2000-10, Vol.69 (4), p.519-521</ispartof><rights>Journal of Neurology, Neurosurgery, and Psychiatry</rights><rights>2000 INIST-CNRS</rights><rights>Copyright: 2000 Journal of Neurology, Neurosurgery, and Psychiatry</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b511t-2550ea0da3115c8b0218c57efdb83b4178479915681a2aa21cbf69bcd0dc7aba3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737142/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1737142/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1485919$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10990515$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rahkonen, Terhi</creatorcontrib><creatorcontrib>Luukkainen-Markkula, Riitta</creatorcontrib><creatorcontrib>Paanila, Satu</creatorcontrib><creatorcontrib>Sivenius, Juhani</creatorcontrib><creatorcontrib>Sulkava, Raimo</creatorcontrib><title>Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>Cognitive decline is commonly stated as one of the main risk factors for delirium. The aim was to assess the importance of a delirium episode as a symptom of an underlying dementia among community dwelling healthy elderly people in a prospective 2 year follow up study. The study patients consisted of 51 people living at home and older than 65 years of age, without severe underlying disorders including diagnosed dementia, admitted consecutively as emergency cases to hospital because of an acute delirious state and followed up for 2 years. The diagnosis of delirium and dementia were based on the DSM-III-R criteria. The community dwelling patients were evaluated and tested annually by a clinical investigator, a geriatric study nurse, and a neuropsychologist. The medical records of the institutionalised patients were also evaluated. Dementia was diagnosed immediately after the assurance that delirium symptoms had subsided in 14 out of 51 subjects (27%) and the additional 14 subjects were diagnosed as being demented during the 2 year follow up, 28 out of 51 patients (55%) altogether. Alzheimer's disease or mixed dementia was diagnosed in 14 out of 51 patients (27%), vascular dementia in 10 (20%), and dementia with Lewy bodies in two (4%). One case of alcoholic dementia and one case of a non-alcoholic hepatic encephalopathia were also found. A delirium episode is often the first sign of dementia requiring attention from medical and social professionals.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aging - physiology</subject><subject>Biological and medical sciences</subject><subject>Brain research</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>delirium</subject><subject>Delirium - physiopathology</subject><subject>Dementia</subject><subject>Dementia - diagnosis</subject><subject>Dementia - physiopathology</subject><subject>elderly</subject><subject>Finland</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Neurology</subject><subject>Neuropsychological Tests</subject><subject>Older people</subject><subject>Short Report</subject><subject>Studies</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkUtv1DAUhSMEotPCki2yBKrYZPB14jxYIKEpL6kqb8TOurGdwUNiBzumzL_Hw4xKYYM3lnw_n3uOTpbdA7oEKKrHG2unZdUuyyWH9ka2gLJq8qKgX25mC0oZywvK6VF2HMKG7k7T3s6OgLYt5cAXWTzTg_EmjkRPJjilCQaCJJi1Ja4n0So9azlrRZQetZ0NEhydXRPpxjFaM2-JutTDYNKTHpT2w5aE2G3Sn_AkCTGy1ehJ74bBXZI4kTBHtb2T3epxCPru4T7JPr14_nH1Kj9_8_L16tl53nGAOWecU41UYQHAZdNRBo3kte5V1xRdCXVT1m0LvGoAGSID2fVV20lFlayxw-Ike7rXnWI3aiVTAI-DmLwZ0W-FQyP-nljzVazdDwF1UUPJksDpQcC771GHWYwmyJQXrXYxiJqxGhirEvjgH3DjorcpXNJqgHOgsKPyPSW9C8Hr_soKULGrU-zqFFUrSpHqTPz96_6v0fv-EvDwAGCQOPQerTThD1c2vP2tc9hrwqx_Xo3RfxNVSsrFxeeV-PCWvr_gZ4V4l_hHe74bN_-x-AtLNMbh</recordid><startdate>20001001</startdate><enddate>20001001</enddate><creator>Rahkonen, Terhi</creator><creator>Luukkainen-Markkula, Riitta</creator><creator>Paanila, Satu</creator><creator>Sivenius, Juhani</creator><creator>Sulkava, Raimo</creator><general>BMJ Publishing Group Ltd</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20001001</creationdate><title>Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study</title><author>Rahkonen, Terhi ; Luukkainen-Markkula, Riitta ; Paanila, Satu ; Sivenius, Juhani ; Sulkava, Raimo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b511t-2550ea0da3115c8b0218c57efdb83b4178479915681a2aa21cbf69bcd0dc7aba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aging - physiology</topic><topic>Biological and medical sciences</topic><topic>Brain research</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>delirium</topic><topic>Delirium - physiopathology</topic><topic>Dementia</topic><topic>Dementia - diagnosis</topic><topic>Dementia - physiopathology</topic><topic>elderly</topic><topic>Finland</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mortality</topic><topic>Neurology</topic><topic>Neuropsychological Tests</topic><topic>Older people</topic><topic>Short Report</topic><topic>Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rahkonen, Terhi</creatorcontrib><creatorcontrib>Luukkainen-Markkula, Riitta</creatorcontrib><creatorcontrib>Paanila, Satu</creatorcontrib><creatorcontrib>Sivenius, Juhani</creatorcontrib><creatorcontrib>Sulkava, Raimo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rahkonen, Terhi</au><au>Luukkainen-Markkula, Riitta</au><au>Paanila, Satu</au><au>Sivenius, Juhani</au><au>Sulkava, Raimo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>2000-10-01</date><risdate>2000</risdate><volume>69</volume><issue>4</issue><spage>519</spage><epage>521</epage><pages>519-521</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>Cognitive decline is commonly stated as one of the main risk factors for delirium. The aim was to assess the importance of a delirium episode as a symptom of an underlying dementia among community dwelling healthy elderly people in a prospective 2 year follow up study. The study patients consisted of 51 people living at home and older than 65 years of age, without severe underlying disorders including diagnosed dementia, admitted consecutively as emergency cases to hospital because of an acute delirious state and followed up for 2 years. The diagnosis of delirium and dementia were based on the DSM-III-R criteria. The community dwelling patients were evaluated and tested annually by a clinical investigator, a geriatric study nurse, and a neuropsychologist. The medical records of the institutionalised patients were also evaluated. Dementia was diagnosed immediately after the assurance that delirium symptoms had subsided in 14 out of 51 subjects (27%) and the additional 14 subjects were diagnosed as being demented during the 2 year follow up, 28 out of 51 patients (55%) altogether. Alzheimer's disease or mixed dementia was diagnosed in 14 out of 51 patients (27%), vascular dementia in 10 (20%), and dementia with Lewy bodies in two (4%). One case of alcoholic dementia and one case of a non-alcoholic hepatic encephalopathia were also found. A delirium episode is often the first sign of dementia requiring attention from medical and social professionals.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>10990515</pmid><doi>10.1136/jnnp.69.4.519</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Aged Aged, 80 and over Aging - physiology Biological and medical sciences Brain research Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases delirium Delirium - physiopathology Dementia Dementia - diagnosis Dementia - physiopathology elderly Finland Follow-Up Studies Humans Male Medical sciences Mortality Neurology Neuropsychological Tests Older people Short Report Studies |
title | Delirium episode as a sign of undetected dementia among community dwelling elderly subjects: a 2 year follow up study |
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