Giant cell arteritis of the cervical radicular vessels presenting with diaphragmatic weakness
The clinical and histopathological details of a patient who succumbed to giant cell arteritis (GCA) of the cervical radicular vessels are described. The initial clinical presentation, with diaphragmatic weakness, has not previously been reported. Normal inflammatory indices and the unusual presentat...
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| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1999-08, Vol.67 (2), p.223-226 |
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| container_title | Journal of neurology, neurosurgery and psychiatry |
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| creator | Burton, E A Winer, J B Barber, P C |
| description | The clinical and histopathological details of a patient who succumbed to giant cell arteritis (GCA) of the cervical radicular vessels are described. The initial clinical presentation, with diaphragmatic weakness, has not previously been reported. Normal inflammatory indices and the unusual presentation prevented diagnosis during life, but GCA should be considered in the differential diagnosis of any unexplained neuropathic or radiculopathic syndrome, as corticosteroid therapy may lead to recovery. This is the first account of the pathological findings in cervical radiculopathy associated with GCA. |
| doi_str_mv | 10.1136/jnnp.67.2.223 |
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The initial clinical presentation, with diaphragmatic weakness, has not previously been reported. Normal inflammatory indices and the unusual presentation prevented diagnosis during life, but GCA should be considered in the differential diagnosis of any unexplained neuropathic or radiculopathic syndrome, as corticosteroid therapy may lead to recovery. This is the first account of the pathological findings in cervical radiculopathy associated with GCA.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.67.2.223</identifier><identifier>PMID: 10406996</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Abdomen ; Aged ; Arteries - pathology ; Biological and medical sciences ; Biopsy ; Blood Vessels - pathology ; diaphragm ; Diaphragm - physiopathology ; Disease ; Fatal Outcome ; giant cell arteritis ; Giant Cell Arteritis - complications ; Giant Cell Arteritis - pathology ; Humans ; Lymphocytes ; Male ; Medical sciences ; Muscle Weakness - etiology ; Neck - blood supply ; Nervous system ; Peripheral Nerves - pathology ; radiculopathy ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; Short Report ; Spinal Cord - pathology ; Spinal Nerve Roots - blood supply ; Veins & arteries</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 1999-08, Vol.67 (2), p.223-226</ispartof><rights>Journal of Neurology, Neurosurgery, and Psychiatry</rights><rights>1999 INIST-CNRS</rights><rights>Copyright: 1999 Journal of Neurology, Neurosurgery, and Psychiatry</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b511t-2fc7a847c6043244ec2f01575dba136e2ec3aceff022e53f54dafca856949cbc3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1736488/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1736488/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,310,311,315,728,781,785,790,791,886,23935,23936,25145,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1884512$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10406996$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burton, E A</creatorcontrib><creatorcontrib>Winer, J B</creatorcontrib><creatorcontrib>Barber, P C</creatorcontrib><title>Giant cell arteritis of the cervical radicular vessels presenting with diaphragmatic weakness</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>The clinical and histopathological details of a patient who succumbed to giant cell arteritis (GCA) of the cervical radicular vessels are described. The initial clinical presentation, with diaphragmatic weakness, has not previously been reported. Normal inflammatory indices and the unusual presentation prevented diagnosis during life, but GCA should be considered in the differential diagnosis of any unexplained neuropathic or radiculopathic syndrome, as corticosteroid therapy may lead to recovery. This is the first account of the pathological findings in cervical radiculopathy associated with GCA.</description><subject>Abdomen</subject><subject>Aged</subject><subject>Arteries - pathology</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>Blood Vessels - pathology</subject><subject>diaphragm</subject><subject>Diaphragm - physiopathology</subject><subject>Disease</subject><subject>Fatal Outcome</subject><subject>giant cell arteritis</subject><subject>Giant Cell Arteritis - complications</subject><subject>Giant Cell Arteritis - pathology</subject><subject>Humans</subject><subject>Lymphocytes</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Muscle Weakness - etiology</subject><subject>Neck - blood supply</subject><subject>Nervous system</subject><subject>Peripheral Nerves - pathology</subject><subject>radiculopathy</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. 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The initial clinical presentation, with diaphragmatic weakness, has not previously been reported. Normal inflammatory indices and the unusual presentation prevented diagnosis during life, but GCA should be considered in the differential diagnosis of any unexplained neuropathic or radiculopathic syndrome, as corticosteroid therapy may lead to recovery. This is the first account of the pathological findings in cervical radiculopathy associated with GCA.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><pmid>10406996</pmid><doi>10.1136/jnnp.67.2.223</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Abdomen Aged Arteries - pathology Biological and medical sciences Biopsy Blood Vessels - pathology diaphragm Diaphragm - physiopathology Disease Fatal Outcome giant cell arteritis Giant Cell Arteritis - complications Giant Cell Arteritis - pathology Humans Lymphocytes Male Medical sciences Muscle Weakness - etiology Neck - blood supply Nervous system Peripheral Nerves - pathology radiculopathy Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Short Report Spinal Cord - pathology Spinal Nerve Roots - blood supply Veins & arteries |
| title | Giant cell arteritis of the cervical radicular vessels presenting with diaphragmatic weakness |
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