A Viral Member of the ERV1/ALR Protein Family Participates in a Cytoplasmic Pathway of Disulfide Bond Formation

Proteins of the ERV1/ALR family are encoded by all eukaryotes and cytoplasmic DNA viruses for which substantial sequence information is available. Nevertheless, the roles of these proteins are imprecisely known. Multiple alignments of ERV1/ALR proteins indicated an invariant C-X-X-C motif, but no si...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2000-10, Vol.97 (22), p.12068-12073
Hauptverfasser:	Senkevich, Tatiana G., White, Christine L., Koonin, Eugene V., Moss, Bernard
Format:	Artikel
Sprache:	eng
Schlagworte:	ALR protein Amino Acid Sequence Antibodies Biological Sciences Cells Cysteine - metabolism Deoxyribonucleic acid Disulfides Disulfides - metabolism DNA DNA-Binding Proteins - chemistry DNA-Binding Proteins - metabolism ERV1 protein Fungal Proteins - chemistry Fungal Proteins - metabolism Genes Mitochondrial Proteins Molecular Sequence Data Neoplasm Proteins Open Reading Frames Oxidoreductases Acting on Sulfur Group Donors Plasmids Proteins Saccharomyces cerevisiae Proteins Sequence Homology, Amino Acid Thiols thioredoxin Vaccinia Vaccinia virus Vaccinia virus - metabolism Virions Viruses
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