TNF-α dependent production of inducible nitric oxide is involved in PGE1 protection against acute liver injury

BACKGROUND Tumour necrosis factor α (TNF-α) and nitric oxide modulate damage in several experimental models of liver injury. We have previously shown that protection against d-galactosamine (D-GalN) induced liver injury by prostaglandin E1 (PGE1) was accompanied by an increase in TNF-α and nitrite/n...

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Veröffentlicht in:	Gut 2000-10, Vol.47 (4), p.553-562
Hauptverfasser:	Muntané, J, Rodríguez, F J, Segado, O, Quintero, A, Lozano, J M, Siendones, E, Pedraza, C A, Delgado, M, O'Valle, F, García, R, Montero, J L, De la Mata, M, Miño, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences d-galactosamine Digestive system Investigative techniques, diagnostic techniques (general aspects) liver injury Medical sciences methylisothiourea nitric oxide Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques prostaglandin E1 tumour necrosis factor α
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