Thiol methyltransferase activity in inflammatory bowel disease

BACKGROUND Luminal anionic sulphide may contribute to epithelial damage in ulcerative colitis. Thiol methyltransferase (TMT) governs sulphide detoxification by the colonic mucosa and circulating erythrocytes. AIMS To measure levels of TMT activity in erythrocytes of surgically treated cases of colit...

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Veröffentlicht in:	Gut 2000-08, Vol.47 (2), p.206-210
Hauptverfasser:	Roediger, W E, Babidge, W J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Amino acids Analysis of Variance Biological and medical sciences Biopsy Blood Case-Control Studies Chromatography, High Pressure Liquid Colitis, Ulcerative - blood Colitis, Ulcerative - enzymology Colon Crohn Disease - blood Crohn Disease - enzymology Crohn's disease Digestive system Enzymes Erythrocytes - enzymology Female Humans hydrogen sulphide Inflammatory bowel disease Investigative techniques, diagnostic techniques (general aspects) Male Males Medical sciences methylation Methyltransferases - metabolism Middle Aged Nitric oxide Ostomy Oxidation Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Rectum - enzymology Rectum - pathology Rodents Sulfur thiol methyltransferase ulcerative colitis
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