Growth failure occurs through a decrease in insulin-like growth factor 1 which is independent of undernutrition in a rat model of colitis

BACKGROUND Linear growth retardation is a frequent complication of inflammatory bowel disease in children. The precise mechanisms causing growth failure are not known. AIMS To determine the relative contribution of reduced calorie intake and inflammation to linear growth delay and to determine the e...

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Veröffentlicht in:	Gut 2000-05, Vol.46 (5), p.695-700
Hauptverfasser:	Ballinger, A B, Azooz, O, El-Haj, T, Poole, S, Farthing, M J G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Colitis - chemically induced Colitis - complications Colitis - physiopathology Dietary Supplements Female Gastroenterology. Liver. Pancreas. Abdomen Growth Disorders - etiology Growth Disorders - metabolism growth retardation Inflammatory bowel disease insulin-like growth factor 1 Insulin-Like Growth Factor I - antagonists & inhibitors Insulin-like growth factors interleukin 6 Interleukin-6 - metabolism Male Medical sciences Nutrition Disorders - complications Nutrition Disorders - physiopathology Other diseases. Semiology Physical growth Rats Rats, Wistar Rodents Stomach. Duodenum. Small intestine. Colon. Rectum. Anus TNBS colitis Trinitrobenzenesulfonic Acid Weight Gain - physiology
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