Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells

BACKGROUND Dietary lectins can alter the proliferation of colonic cells. Differentiation is regulated by adhesion molecules which, being glycosylated, are targets for lectin binding. AIMS To examine the effects of dietary lectins on differentiation, adhesion, and proliferation of colorectal cancer c...

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Veröffentlicht in:	Gut 1999-05, Vol.44 (5), p.709-714
Hauptverfasser:	Jordinson, M, El-Hariry, I, Calnan, D, Calam, J, Pignatelli, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - pathology Antigens, Neoplasm - metabolism Biological and medical sciences Blotting, Western Cell Adhesion Cell adhesion & migration Cell Adhesion Molecules - metabolism Cell Differentiation - drug effects Cell Division - drug effects colon cancer Colorectal cancer Colorectal Neoplasms - pathology Cytotoxicity differentiation Digestive system Epithelial Cell Adhesion Molecule Fabaceae - chemistry Gastrointestinal Cancer Humans Immunoglobulins Investigative techniques, diagnostic techniques (general aspects) Lectins Lectins - pharmacology Medical sciences Membranes Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Plant Lectins Plants, Medicinal polarity proliferation Proteins Studies Sugar Tumor Cells, Cultured - drug effects Tumors
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