Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode

Aims: To compare the efficacy of terbutaline sulphate delivered via Turbuhaler with a pressurised metered dose inhaler (pMDI) connected to Nebuhaler spacer in a population of asthmatic children presenting to emergency departments because of an acute episode of asthma. Methods: Randomised double blin...

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Veröffentlicht in:	Archives of disease in childhood 2003-04, Vol.88 (4), p.319-323
Hauptverfasser:	Drblik, S, Lapierre, G, Thivierge, R, Turgeon, J, Gaudreault, P, Cummins-McManus, B, Verdy, I, Haddon, J, Lee, J, Spier, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Administration, Inhalation Adolescent Adrenergic beta-Agonists - administration & dosage Aqueous solutions Asthma Asthma - drug therapy Asthma - physiopathology Biological and medical sciences Bronchodilator Agents - administration & dosage Care and treatment Child Children Delivery Systems Diseases Dosage and administration Double-Blind Method DPI Drug Delivery Systems Drug therapy dry powder inhaler Emergencies Evaluation Female FEV1 Forced Expiratory Volume - drug effects forced expiratory volume in one second Guidelines Heart rate Heart Rate - drug effects Hospitals Humans inhaler Inhalers intention to treat ITT Male Medical sciences Metered Dose Inhalers nebuhaler Nebulizers and Vaporizers Original Patients peak expiratory flow peak inspiratory flow Pediatric diseases PEF Pharmaceutical industry Pharmacology. Drug treatments PIF pMDI PNV predicted normal value pressurised metered dose inhaler Product development Product/service Evaluations Respiratory system Respiratory therapy spacer SpO2 Statistical Analysis Studies Sulfates Terbutaline Terbutaline - administration & dosage Test Results time transcutaneous oxygen saturation turbuhaler
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