Evidence for a Familial Pregnancy-Induced Hypertension Locus in the eNOS-Gene Region

Pregnancy-induced hypertension may be regarded as a manifestation of endothelial-cell dysfunction. The role of the eNOS gene in the development of a familial pregnancy-induced hypertension was evaluated by analysis of linkage among affected sisters and in multiplex families ( n = 50). Markers from a...

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Veröffentlicht in:	American journal of human genetics 1997-08, Vol.61 (2), p.354-362
Hauptverfasser:	Arngrímsson, Reynir, Hayward, Caroline, Nadaud, Sophie, Baldursdóttir, Asdis, Walker, James J., Liston, Wang A., Bjarnadóttir, Ragnheiür I., Brock, David J.H., Geirsson, Reynir T., Connor, J. Michael, Soubrier, Florent
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Biological and medical sciences Chromosomes, Human, Pair 7 - genetics Diseases of mother, fetus and pregnancy Endothelium, Vascular - enzymology Female Genes Genetic Linkage Gynecology. Andrology. Obstetrics Humans Iceland - epidemiology Life Sciences Likelihood Functions Lod Score Matched-Pair Analysis Medical sciences Microsatellite Repeats Molecular Epidemiology Nitric Oxide Synthase - genetics Pre-Eclampsia - enzymology Pre-Eclampsia - epidemiology Pre-Eclampsia - genetics Pregnancy Pregnancy Complications, Cardiovascular - enzymology Pregnancy Complications, Cardiovascular - epidemiology Pregnancy Complications, Cardiovascular - etiology Pregnancy. Fetus. Placenta Scotland - epidemiology Statistics, Nonparametric
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