The effect of tropolone on the formation of 3,4‐dihydroxyphenylacetic acid and 4‐hydroxy‐3‐methoxyphenylacetic acid in the brain of the mouse

1 The development of a very sensitive and specific fluorimetric assay for 3,4‐dihydroxyphenylacetic acid has made it possible to measure how inhibitors of the enzyme catechol‐O‐methyl transferase affect the relative concentrations of this acid and its O‐methylated derivative 4‐hydroxy‐3‐methoxypheny...

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Veröffentlicht in:	British journal of pharmacology 1969-05, Vol.36 (1), p.107-115
Hauptverfasser:	MURPHY, G. F., ROBINSON, D., SHARMAN, D. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Cycloparaffins - pharmacology Dihydroxyphenylalanine - pharmacology Female Fluorometry Ketones - pharmacology Mice Phenylacetates - analysis Phenylacetates - biosynthesis Probenecid - pharmacology
Online-Zugang:	Volltext
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