Transcription increases multiple spontaneous point mutations in Salmonella enterica

The spontaneous rate of G·C→A·T mutations and a hotspot T·A→G·C transversion are known to increase with the frequency of transcription—increases that have been ascribed primarily to processes that affect only these specific mutations. To investigate how transcription induces other spontaneous point...

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Veröffentlicht in:	Nucleic acids research 2003-08, Vol.31 (15), p.4517-4522
Hauptverfasser:	Hudson, Richard Ellis, Bergthorsson, Ulfar, Ochman, Howard
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Resistance, Bacterial Genes, Bacterial Point Mutation Rifampin - pharmacology Salmonella Salmonella enterica - drug effects Salmonella enterica - genetics Transcription, Genetic
Online-Zugang:	Volltext
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