Human Neutrophil Elastase Induces Hypersecretion of Mucin from Well-Differentiated Human Bronchial Epithelial Cells in Vitro via a Protein Kinase Cδ-Mediated Mechanism

The presence of mucus obstruction and neutrophil-predominant inflammation in several lung disorders, such as cystic fibrosis, suggests a relationship between neutrophils and excess mucus production. Mechanisms of human neutrophil elastase (HNE)-induced mucin secretion by well-differentiated normal h...

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Veröffentlicht in:The American journal of pathology 2005-09, Vol.167 (3), p.651-661
Hauptverfasser: Park, Jin-Ah, He, Fang, Martin, Linda D., Li, Yuehua, Chorley, Brian N., Adler, Kenneth B.
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Sprache:eng
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