Sec-Mediated Transport of Posttranslationally Dehydrated Peptides in Lactococcus lactis

Nisin is a lanthionine-containing antimicrobial peptide produced by Lactococcus lactis. Its (methyl)lanthionines are introduced by two posttranslational enzymatic steps involving the dehydratase NisB, which dehydrates serine and threonine residues, and the cyclase NisC, which couples these dehydrate...

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Veröffentlicht in:	Applied and Environmental Microbiology 2006-12, Vol.72 (12), p.7626-7633
Hauptverfasser:	Kuipers, Anneke, Wierenga, Jenny, Rink, Rick, Kluskens, Leon D, Driessen, Arnold J.M, Kuipers, Oscar P, Moll, Gert N
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporters Adenosine Triphosphatases - metabolism Amino acids Anti-Bacterial Agents - biosynthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - metabolism Bacterial Proteins - metabolism Biological and medical sciences Biotechnology - methods Enzymes Enzymology and Protein Engineering Fundamental and applied biological sciences. Psychology Lactococcus lactis Lactococcus lactis - metabolism Membrane Proteins - metabolism Membrane Transport Proteins - metabolism Microbiology Nisin - biosynthesis Nisin - chemistry Nisin - metabolism Peptides Peptides - chemistry Peptides - metabolism Protein Processing, Post-Translational Protein Sorting Signals SEC Translocation Channels SecA Proteins Studies
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