mtDNA sequences suggest a recent evolutionary divergence for Beringian and Northern North American populations

Conventional descriptions of the pattern and process of human entry into the New World from Asia are incomplete and controversial. In order to gain an evolutionary insight into this process, we have sequenced the control region of mtDNA in samples of contemporary tribal populations of eastern Siberi...

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Veröffentlicht in:American journal of human genetics 1993-09, Vol.53 (3), p.549-562
Hauptverfasser: SHIELDS, G. F, SCHMIECHEN, A. M, FRAZIER, B. L, REDD, A, VOEVODA, M. I, REED, J. K, WARD, R. H
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container_end_page 562
container_issue 3
container_start_page 549
container_title American journal of human genetics
container_volume 53
creator SHIELDS, G. F
SCHMIECHEN, A. M
FRAZIER, B. L
REDD, A
VOEVODA, M. I
REED, J. K
WARD, R. H
description Conventional descriptions of the pattern and process of human entry into the New World from Asia are incomplete and controversial. In order to gain an evolutionary insight into this process, we have sequenced the control region of mtDNA in samples of contemporary tribal populations of eastern Siberia, Alaska, and Greenland and have compared them with those of Amerind speakers of the Pacific Northwest and with those of the Altai of central Siberia. Specifically, we have analyzed sequence diversity in 33 mitochondrial lineages identified in 90 individuals belonging to five Circumpolar populations of Beringia, North America, and Greenland: Chukchi from Siberia, Inupiaq Eskimos and Athapaskans from Alaska, Eskimos from West Greenland, and Haida from Canada. Hereafter, we refer to these five populations as "Circumarctic peoples." These data were then compared with the sequence diversity in 47 mitochondrial lineages identified in a sample of 145 individuals from three Amerind-speaking tribes (Bella Coola, Nuu-Chah-Nulth, and Yakima) of the Pacific Northwest, plus 16 mitochondrial lineages identified in a sample of 17 Altai from central Siberia. Sequence diversity within and among Circumarctic populations is considerably less than the sequence diversity observed within and among the three Amerind tribes. The similarity of sequences found among the geographically dispersed Circumarctic groups, plus the small values of mean pairwise sequence differences within Circumarctic populations, suggest a recent and rapid evolutionary radiation of these populations. In addition, Circumarctic populations lack the 9-bp deletion which has been used to trace various migrations out of Asia, while populations of southeastern Siberia possess this deletion. On the basis of these observations, while the evolutionary affinities of Native Americans extend west to the Circumarctic populations of eastern Siberia, they do not include the Altai of central Siberia.
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F ; SCHMIECHEN, A. M ; FRAZIER, B. L ; REDD, A ; VOEVODA, M. I ; REED, J. K ; WARD, R. H</creator><creatorcontrib>SHIELDS, G. F ; SCHMIECHEN, A. M ; FRAZIER, B. L ; REDD, A ; VOEVODA, M. I ; REED, J. K ; WARD, R. H</creatorcontrib><description>Conventional descriptions of the pattern and process of human entry into the New World from Asia are incomplete and controversial. In order to gain an evolutionary insight into this process, we have sequenced the control region of mtDNA in samples of contemporary tribal populations of eastern Siberia, Alaska, and Greenland and have compared them with those of Amerind speakers of the Pacific Northwest and with those of the Altai of central Siberia. Specifically, we have analyzed sequence diversity in 33 mitochondrial lineages identified in 90 individuals belonging to five Circumpolar populations of Beringia, North America, and Greenland: Chukchi from Siberia, Inupiaq Eskimos and Athapaskans from Alaska, Eskimos from West Greenland, and Haida from Canada. Hereafter, we refer to these five populations as "Circumarctic peoples." These data were then compared with the sequence diversity in 47 mitochondrial lineages identified in a sample of 145 individuals from three Amerind-speaking tribes (Bella Coola, Nuu-Chah-Nulth, and Yakima) of the Pacific Northwest, plus 16 mitochondrial lineages identified in a sample of 17 Altai from central Siberia. Sequence diversity within and among Circumarctic populations is considerably less than the sequence diversity observed within and among the three Amerind tribes. The similarity of sequences found among the geographically dispersed Circumarctic groups, plus the small values of mean pairwise sequence differences within Circumarctic populations, suggest a recent and rapid evolutionary radiation of these populations. In addition, Circumarctic populations lack the 9-bp deletion which has been used to trace various migrations out of Asia, while populations of southeastern Siberia possess this deletion. 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The similarity of sequences found among the geographically dispersed Circumarctic groups, plus the small values of mean pairwise sequence differences within Circumarctic populations, suggest a recent and rapid evolutionary radiation of these populations. In addition, Circumarctic populations lack the 9-bp deletion which has been used to trace various migrations out of Asia, while populations of southeastern Siberia possess this deletion. On the basis of these observations, while the evolutionary affinities of Native Americans extend west to the Circumarctic populations of eastern Siberia, they do not include the Altai of central Siberia.</abstract><cop>Chicago, IL</cop><pub>University of Chicago Press</pub><pmid>8352271</pmid><tpages>14</tpages></addata></record>
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source MEDLINE; Elsevier ScienceDirect Journals Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central
subjects Alaska
Arctic Regions
Asian Continental Ancestry Group - genetics
Base Sequence
Biological and medical sciences
Biological evolution
DNA
DNA, Mitochondrial - analysis
DNA, Mitochondrial - genetics
Female
Fundamental and applied biological sciences. Psychology
Genetic Variation
Genetics of eukaryotes. Biological and molecular evolution
Greenland
Humans
Indians, North American - genetics
Inuits - genetics
Male
man
mitochondria
Molecular Sequence Data
Northwestern United States
Phylogeny
population genetics
Sequence Analysis, DNA
Sequence Deletion
Siberia
title mtDNA sequences suggest a recent evolutionary divergence for Beringian and Northern North American populations
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