Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain

Oxytocin is released from supraoptic magnocellular neurones and is thought to act at presynaptic receptors to inhibit transmitter release. We now show that this effect is mediated by endocannabinoids, but that oxytocin nonetheless plays an important role in endocannabinoid signalling. WIN55,212-2, a...

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Veröffentlicht in:	The Journal of physiology 2004-09, Vol.559 (2), p.611-624
Hauptverfasser:	Hirasawa, Michiru, Schwab, Yannick, Natah, Sirajedin, Hillard, Cecilia J., Mackie, Ken, Sharkey, Keith A., Pittman, Quentin J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autocrine Communication - drug effects Autocrine Communication - physiology Benzoxazines Biochemistry, Molecular Biology Brain - drug effects Brain - metabolism Cannabinoid Receptor Modulators - metabolism Dendrites - drug effects Dendrites - metabolism In Vitro Techniques Life Sciences Male Morpholines - pharmacology Naphthalenes - pharmacology Neurons, Afferent - drug effects Neurons, Afferent - metabolism Neurotransmitter Agents - metabolism Nifedipine - pharmacology Rats Rats, Sprague-Dawley Research Papers
Online-Zugang:	Volltext
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