Measurement of activity of urea resistant neutrophil alkaline phosphatase as an antenatal screening test for Down's syndrome

OBJECTIVE--To investigate the value of measuring maternal urea resistant neutrophil alkaline phosphatase activity as an antenatal screening test for Down's syndrome. DESIGN--Case-control study of blood samples collected at nine to 27 weeks of pregnancy. SETTING--Antenatal clinics in London and...

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Veröffentlicht in:	BMJ 1990-11, Vol.301 (6759), p.1024-1026
Hauptverfasser:	Cuckle, H S, Wald, N J, Goodburn, S F, Sneddon, J, Amess, J A, Dunn, S C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alkaline Phosphatase - blood Amniocentesis Biological and medical sciences Blood Case-Control Studies Chorionic villi sampling Clinical Enzyme Tests Down syndrome Down Syndrome - diagnosis Enzyme activity Female Fetal Diseases - diagnosis Fetus Humans Medical genetics Medical sciences Neutrophils Neutrophils - enzymology Phosphatases Pregnancy Prenatal Diagnosis Screening tests Time Factors Urea
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