Autoinsertion of soluble oligomers of Alzheimer's A beta (1-42) peptide into cholesterol-containing membranes is accompanied by relocation of the sterol towards the bilayer surface

Soluble Alzheimer's A beta oligomers autoinsert into neuronal cell membranes, contributing to the pathology of Alzheimer's Disease (AD), and elevated serum cholesterol is a risk factor for AD, but the reason is unknown. We investigated potential connections between these two observations a...

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Veröffentlicht in:	BMC structural biology 2006-10, Vol.6 (1), p.21-21
Hauptverfasser:	Ashley, Richard H, Harroun, Thad A, Hauss, Thomas, Breen, Kieran C, Bradshaw, Jeremy P
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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