Ascending cholangitis after successful surgical repair of biliary atresia
Since the introduction of hepatic porto-enterostomy, encouraging results have been obtained in treating extrahepatic biliary atresia, particularly in the case of infants with atresia or agenesis of the extrahepatic ducts, who would not previously have been considered amenable to surgery. Out of 17 s...
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Veröffentlicht in: | Archives of disease in childhood 1973-09, Vol.48 (9), p.697-703 |
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creator | Kobayashi, Akio Utsunomiya, Takeko Ohbe, Yoshiro Shimizu, Kohichi |
description | Since the introduction of hepatic porto-enterostomy, encouraging results have been obtained in treating extrahepatic biliary atresia, particularly in the case of infants with atresia or agenesis of the extrahepatic ducts, who would not previously have been considered amenable to surgery. Out of 17 successfully repaired cases who had shown good bile excretion after surgery and who had no jaundice, 8 (47%) developed ascending cholangitis 3½ to 8½ months after surgery. Cholangitis of this type formed a recognizable picture, with repeated attacks of fever, reappearance of obstructive jaundice, raised erythrocyte sedimentation rate, leucocytosis with shift to the left, and anaemia. The condition was often resistant to antibiotic therapy, and was fatal in 3 cases. |
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Out of 17 successfully repaired cases who had shown good bile excretion after surgery and who had no jaundice, 8 (47%) developed ascending cholangitis 3½ to 8½ months after surgery. Cholangitis of this type formed a recognizable picture, with repeated attacks of fever, reappearance of obstructive jaundice, raised erythrocyte sedimentation rate, leucocytosis with shift to the left, and anaemia. The condition was often resistant to antibiotic therapy, and was fatal in 3 cases.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/adc.48.9.697</identifier><identifier>PMID: 4200280</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Anemia - complications ; Anti-Bacterial Agents - therapeutic use ; Bile Ducts - abnormalities ; Biliary Fistula ; Biliary Tract - abnormalities ; Biliary Tract Surgical Procedures ; Blood Sedimentation ; Cholangitis - drug therapy ; Cholangitis - etiology ; Cholestasis - complications ; Female ; Humans ; Infant ; Infant, Newborn ; Leukocyte Count ; Leukocytosis - complications ; Male ; Original ; Postoperative Complications</subject><ispartof>Archives of disease in childhood, 1973-09, Vol.48 (9), p.697-703</ispartof><rights>Copyright BMJ Publishing Group LTD Sep 1973</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b477t-43d00be5dffb415d66520c66575248e2bec4fd5ccbfb31fa5c521ce9a13b8e53</citedby><cites>FETCH-LOGICAL-b477t-43d00be5dffb415d66520c66575248e2bec4fd5ccbfb31fa5c521ce9a13b8e53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1648501/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1648501/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4200280$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kobayashi, Akio</creatorcontrib><creatorcontrib>Utsunomiya, Takeko</creatorcontrib><creatorcontrib>Ohbe, Yoshiro</creatorcontrib><creatorcontrib>Shimizu, Kohichi</creatorcontrib><title>Ascending cholangitis after successful surgical repair of biliary atresia</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>Since the introduction of hepatic porto-enterostomy, encouraging results have been obtained in treating extrahepatic biliary atresia, particularly in the case of infants with atresia or agenesis of the extrahepatic ducts, who would not previously have been considered amenable to surgery. Out of 17 successfully repaired cases who had shown good bile excretion after surgery and who had no jaundice, 8 (47%) developed ascending cholangitis 3½ to 8½ months after surgery. Cholangitis of this type formed a recognizable picture, with repeated attacks of fever, reappearance of obstructive jaundice, raised erythrocyte sedimentation rate, leucocytosis with shift to the left, and anaemia. The condition was often resistant to antibiotic therapy, and was fatal in 3 cases.</description><subject>Anemia - complications</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Bile Ducts - abnormalities</subject><subject>Biliary Fistula</subject><subject>Biliary Tract - abnormalities</subject><subject>Biliary Tract Surgical Procedures</subject><subject>Blood Sedimentation</subject><subject>Cholangitis - drug therapy</subject><subject>Cholangitis - etiology</subject><subject>Cholestasis - complications</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Leukocyte Count</subject><subject>Leukocytosis - complications</subject><subject>Male</subject><subject>Original</subject><subject>Postoperative Complications</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kc9LHDEUx0NR7LrtrVdhQKgXZ5vfk7kUZLEqiJYi0tsjySRrtrMzazIj7X_fyC6LevCSBL6fvPd974vQF4JnhDD5TTd2xtWsnsm6-oAmhEtVUsz5HppgjFlZK6U-osOUlhgTqhQ7QAecYkwVnqCrs2Rd14RuUdiHvtXdIgwhFdoPLhZptNal5Mc2P-MiWN0W0a11iEXvCxPaoOO_Qg_RpaA_oX2v2-Q-b-8puvtxfje_LK9vL67mZ9el4VU1lJw1GBsnGu8NJ6KRUlBs81kJypWjxlnuG2Gt8YYRr4UVlFhXa8KMcoJN0fdN2fVoVq7J5oeoW1jHsMpmoNcBXitdeIBF_wREciUwyQW-bgvE_nF0aYBVyDto8-yuHxMoigkXkmfw-A247MfY5dmAVHnXjBFZZ-p0Q9nYpxSd31khGJ7zgZwPcAU1PP-ZoqOX9nfwNpCslxs9pMH93ck6_gFZsUrAzf0cftKK_JY3v-A-8ycb3qyW73f-D0CoqQU</recordid><startdate>19730901</startdate><enddate>19730901</enddate><creator>Kobayashi, Akio</creator><creator>Utsunomiya, Takeko</creator><creator>Ohbe, Yoshiro</creator><creator>Shimizu, Kohichi</creator><general>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19730901</creationdate><title>Ascending cholangitis after successful surgical repair of biliary atresia</title><author>Kobayashi, Akio ; Utsunomiya, Takeko ; Ohbe, Yoshiro ; Shimizu, Kohichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b477t-43d00be5dffb415d66520c66575248e2bec4fd5ccbfb31fa5c521ce9a13b8e53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Anemia - complications</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Bile Ducts - abnormalities</topic><topic>Biliary Fistula</topic><topic>Biliary Tract - abnormalities</topic><topic>Biliary Tract Surgical Procedures</topic><topic>Blood Sedimentation</topic><topic>Cholangitis - drug therapy</topic><topic>Cholangitis - etiology</topic><topic>Cholestasis - complications</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Leukocyte Count</topic><topic>Leukocytosis - complications</topic><topic>Male</topic><topic>Original</topic><topic>Postoperative Complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kobayashi, Akio</creatorcontrib><creatorcontrib>Utsunomiya, Takeko</creatorcontrib><creatorcontrib>Ohbe, Yoshiro</creatorcontrib><creatorcontrib>Shimizu, Kohichi</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Education Periodicals</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Education Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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Out of 17 successfully repaired cases who had shown good bile excretion after surgery and who had no jaundice, 8 (47%) developed ascending cholangitis 3½ to 8½ months after surgery. Cholangitis of this type formed a recognizable picture, with repeated attacks of fever, reappearance of obstructive jaundice, raised erythrocyte sedimentation rate, leucocytosis with shift to the left, and anaemia. The condition was often resistant to antibiotic therapy, and was fatal in 3 cases.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><pmid>4200280</pmid><doi>10.1136/adc.48.9.697</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Anemia - complications Anti-Bacterial Agents - therapeutic use Bile Ducts - abnormalities Biliary Fistula Biliary Tract - abnormalities Biliary Tract Surgical Procedures Blood Sedimentation Cholangitis - drug therapy Cholangitis - etiology Cholestasis - complications Female Humans Infant Infant, Newborn Leukocyte Count Leukocytosis - complications Male Original Postoperative Complications |
title | Ascending cholangitis after successful surgical repair of biliary atresia |
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