Exposure-response relationships for saquinavir, zidovudine, and zalcitabine in combination therapy
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 1997-11, Vol.41 (11), p.2433-2438 |
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| container_title | Antimicrobial Agents and Chemotherapy |
| container_volume | 41 |
| creator | VANHOVE, G. F GRIES, J.-M VEROTTA, D SHEINER, L. B COOMBS, R COLLIER, A. C BLASCHKE, T. F |
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| doi_str_mv | 10.1128/aac.41.11.2433 |
| format | Article |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.41.11.2433</identifier><identifier>PMID: 9371346</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Adult ; AIDS/HIV ; Anti-HIV Agents ; Anti-HIV Agents - blood ; Anti-HIV Agents - pharmacokinetics ; Anti-HIV Agents - therapeutic use ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral agents ; Area Under Curve ; Biological and medical sciences ; CD4 Lymphocyte Count - drug effects ; Clinical Trial ; Clinical Trial, Phase II ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Female ; HIV Infections ; HIV Infections - drug therapy ; HIV Infections - immunology ; Humans ; Male ; Medical sciences ; Middle Aged ; Multicenter Study ; Pharmacology. Drug treatments ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S ; RNA, Viral - blood ; Saquinavir ; Saquinavir - blood ; Saquinavir - pharmacokinetics ; Saquinavir - therapeutic use ; Zalcitabine ; Zalcitabine - blood ; Zalcitabine - pharmacokinetics ; Zalcitabine - therapeutic use ; Zidovudine ; Zidovudine - blood ; Zidovudine - pharmacokinetics ; Zidovudine - therapeutic use</subject><ispartof>Antimicrobial Agents and Chemotherapy, 1997-11, Vol.41 (11), p.2433-2438</ispartof><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a573t-42a632ded1d5bfc32a3a3211776feb09a9c1f578b65bdd3e90a720a85dbb272c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC164141/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC164141/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2054500$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9371346$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VANHOVE, G. F</creatorcontrib><creatorcontrib>GRIES, J.-M</creatorcontrib><creatorcontrib>VEROTTA, D</creatorcontrib><creatorcontrib>SHEINER, L. B</creatorcontrib><creatorcontrib>COOMBS, R</creatorcontrib><creatorcontrib>COLLIER, A. C</creatorcontrib><creatorcontrib>BLASCHKE, T. F</creatorcontrib><title>Exposure-response relationships for saquinavir, zidovudine, and zalcitabine in combination therapy</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Services
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</description><subject>Adult</subject><subject>AIDS/HIV</subject><subject>Anti-HIV Agents</subject><subject>Anti-HIV Agents - blood</subject><subject>Anti-HIV Agents - pharmacokinetics</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral agents</subject><subject>Area Under Curve</subject><subject>Biological and medical sciences</subject><subject>CD4 Lymphocyte Count - drug effects</subject><subject>Clinical Trial</subject><subject>Clinical Trial, Phase II</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Therapy, Combination</subject><subject>Female</subject><subject>HIV Infections</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - immunology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multicenter Study</subject><subject>Pharmacology. Drug treatments</subject><subject>Randomized Controlled Trial</subject><subject>Research Support, Non-U.S. Gov't</subject><subject>Research Support, U.S. Gov't, P.H.S</subject><subject>RNA, Viral - blood</subject><subject>Saquinavir</subject><subject>Saquinavir - blood</subject><subject>Saquinavir - pharmacokinetics</subject><subject>Saquinavir - therapeutic use</subject><subject>Zalcitabine</subject><subject>Zalcitabine - blood</subject><subject>Zalcitabine - pharmacokinetics</subject><subject>Zalcitabine - therapeutic use</subject><subject>Zidovudine</subject><subject>Zidovudine - blood</subject><subject>Zidovudine - pharmacokinetics</subject><subject>Zidovudine - therapeutic use</subject><issn>0066-4804</issn><issn>1098-6596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk1v1DAQhi0EKkvhyg0pQogLzeLvxAcOq1UpSJW4wNma2E7jKolTO9nS_npcdrVqD4iTX3ued2bsMUJvCV4TQuvPAGbNSdZryhl7hlYEq7qUQsnnaIWxlCWvMX-JXqV0jfNeKHyCThSrCONyhZrz31NIS3RldGkKY3JFdD3MPsvOT6loQywS3Cx-hJ2PZ8W9t2G3WD-6swJGW9xDb_wMTT4o_FiYMGT511_MnYsw3b1GL1rok3tzWE_Rr6_nP7ffyssfF9-3m8sSRMXmklOQjFpniRVNaxgFBowSUlWydQ1WoAxpRVU3UjTWMqcwVBRDLWzT0Ioadoq-7PNOSzM4a9w4R-j1FP0A8U4H8PppZPSdvgo7TSQnnGT_x4M_hpvFpVkPPhnX9zC6sCRdKY4ZFuq_IJEid61kBtd70MSQUnTtsRmC9cP09Gaz1ZxkrR-mlw2f9gZIA9XXYYljfrF_0-8eX_iY_DDcHP9wiEMy0LcRRuPTEaNYcIFxxt7vsc5fdbc-Op2r6_yvHtf6Axdovdk</recordid><startdate>19971101</startdate><enddate>19971101</enddate><creator>VANHOVE, G. 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F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a573t-42a632ded1d5bfc32a3a3211776feb09a9c1f578b65bdd3e90a720a85dbb272c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Adult</topic><topic>AIDS/HIV</topic><topic>Anti-HIV Agents</topic><topic>Anti-HIV Agents - blood</topic><topic>Anti-HIV Agents - pharmacokinetics</topic><topic>Anti-HIV Agents - therapeutic use</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral agents</topic><topic>Area Under Curve</topic><topic>Biological and medical sciences</topic><topic>CD4 Lymphocyte Count - drug effects</topic><topic>Clinical Trial</topic><topic>Clinical Trial, Phase II</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Therapy, Combination</topic><topic>Female</topic><topic>HIV Infections</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - immunology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multicenter Study</topic><topic>Pharmacology. Drug treatments</topic><topic>Randomized Controlled Trial</topic><topic>Research Support, Non-U.S. Gov't</topic><topic>Research Support, U.S. Gov't, P.H.S</topic><topic>RNA, Viral - blood</topic><topic>Saquinavir</topic><topic>Saquinavir - blood</topic><topic>Saquinavir - pharmacokinetics</topic><topic>Saquinavir - therapeutic use</topic><topic>Zalcitabine</topic><topic>Zalcitabine - blood</topic><topic>Zalcitabine - pharmacokinetics</topic><topic>Zalcitabine - therapeutic use</topic><topic>Zidovudine</topic><topic>Zidovudine - blood</topic><topic>Zidovudine - pharmacokinetics</topic><topic>Zidovudine - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>VANHOVE, G. F</creatorcontrib><creatorcontrib>GRIES, J.-M</creatorcontrib><creatorcontrib>VEROTTA, D</creatorcontrib><creatorcontrib>SHEINER, L. B</creatorcontrib><creatorcontrib>COOMBS, R</creatorcontrib><creatorcontrib>COLLIER, A. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>9371346</pmid><doi>10.1128/aac.41.11.2433</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 1997-11, Vol.41 (11), p.2433-2438 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_164141 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Adult AIDS/HIV Anti-HIV Agents Anti-HIV Agents - blood Anti-HIV Agents - pharmacokinetics Anti-HIV Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Area Under Curve Biological and medical sciences CD4 Lymphocyte Count - drug effects Clinical Trial Clinical Trial, Phase II Dose-Response Relationship, Drug Drug Therapy, Combination Female HIV Infections HIV Infections - drug therapy HIV Infections - immunology Humans Male Medical sciences Middle Aged Multicenter Study Pharmacology. Drug treatments Randomized Controlled Trial Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S RNA, Viral - blood Saquinavir Saquinavir - blood Saquinavir - pharmacokinetics Saquinavir - therapeutic use Zalcitabine Zalcitabine - blood Zalcitabine - pharmacokinetics Zalcitabine - therapeutic use Zidovudine Zidovudine - blood Zidovudine - pharmacokinetics Zidovudine - therapeutic use |
| title | Exposure-response relationships for saquinavir, zidovudine, and zalcitabine in combination therapy |
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