Topical problems and basic developmental trends of investigations concerning the embryotoxic and teratogenic effect of environmental chemicals

Assessed is the importance of embryotoxic and teratogenic studies of environmental Chemicals to the development of effective methods to prevent embryo disorders and congenital defects. Adequate methodological approaches for testing the teratogenicity and embryotoxicity of chemical substances must be...

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Veröffentlicht in:Environmental health perspectives 1979-06, Vol.30, p.99-103
1. Verfasser: Dyban, A.P
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description Assessed is the importance of embryotoxic and teratogenic studies of environmental Chemicals to the development of effective methods to prevent embryo disorders and congenital defects. Adequate methodological approaches for testing the teratogenicity and embryotoxicity of chemical substances must be developed. The criteria for teratogenicity must be broadened; a wider range of biological models should be used; and factors influencing teratogenic activity should be identified.
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source MEDLINE; DOAJ Directory of Open Access Journals; PubMed Central Open Access; JSTOR Archive Collection A-Z Listing; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Animals
Chemical hazards
Embryo, Mammalian - drug effects
Embryogenesis
Embryos
Environmental Pollutants
Fetus
Humans
Medical genetics
Molecular structure
Rats
Species Specificity
Teratogenicity
Teratogens
Teratology
US-USSR Cooperative Program on Environmental Health
title Topical problems and basic developmental trends of investigations concerning the embryotoxic and teratogenic effect of environmental chemicals
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