Dipterex teratogenicity in the rat, hamster, and mouse when given by gavage

Dipterex was teratogenic after administration by gavage (t.i.d.) at a dose level of 480 mg/kg-day to the CD rat on days 6 through 15 of gestation, but not when administered only on days 8 or 10 of gestation. A positive teratogenic response also occurred in the hamster after administration on days 7...

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Veröffentlicht in:	Environmental health perspectives 1979-06, Vol.30, p.105-113
Hauptverfasser:	Staples, R.E, Goulding, E.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cholinesterase Inhibitors Cleft palate Cricetinae Dosage Dose-Response Relationship, Drug Female Fetus Fetus - drug effects Food consumption Gavage Gestation period Gestational Age Male Mice Pregnancy Rats Reproduction Species Specificity Teratogenicity Teratogens Trichlorfon - administration & dosage Trichlorfon - toxicity US-USSR Cooperative Program on Environmental Health
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