RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase δ

In fulfilling its biosynthetic roles in nuclear replication and in several types of repair, DNA polymerase δ (pol δ) is assisted by replication protein A (RPA), the single-stranded DNA-binding protein complex, and by the processivity clamp proliferating cell nuclear antigen (PCNA). Here we report th...

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Veröffentlicht in:	Nucleic acids research 2006-09, Vol.34 (16), p.4335-4341
Hauptverfasser:	Fortune, John M, Stith, Carrie M, Kissling, Grace E, Burgers, Peter M.J, Kunkel, Thomas A
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Pair Mismatch DNA - biosynthesis DNA - chemistry DNA Polymerase III - metabolism Fungal Proteins - metabolism Nucleic Acid Enzymes Nucleotides - metabolism Proliferating Cell Nuclear Antigen - metabolism Repetitive Sequences, Nucleic Acid Replication Protein A - metabolism Sequence Deletion
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