Analysis of Shape, Fluctuations, and Dynamics in Intermembrane Junctions
A dynamic-elastic model for weakly adhered intermembrane junctions is presented. Helfrich membrane energetics coupled to hydrodynamic modes of the surrounding solvent reproduce the average shape, fluctuations, and dynamics of these junctions as measured experimentally. Comparison between numerical r...
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| Veröffentlicht in: | Biophysical journal 2006-11, Vol.91 (10), p.3600-3606 |
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| creator | Lin, Lawrence C.-L. Groves, Jay T. Brown, Frank L.H. |
| description | A dynamic-elastic model for weakly adhered intermembrane junctions is presented. Helfrich membrane energetics coupled to hydrodynamic modes of the surrounding solvent reproduce the average shape, fluctuations, and dynamics of these junctions as measured experimentally. Comparison between numerical results and experimental data provides the first direct measure of surface tension in these systems (0.01–0.06
dyn/cm). The measurements suggest bilayer-bilayer adhesion energetics as the dominant source of surface tension in the experimental systems. |
| doi_str_mv | 10.1529/biophysj.106.091843 |
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dyn/cm). The measurements suggest bilayer-bilayer adhesion energetics as the dominant source of surface tension in the experimental systems.</description><identifier>ISSN: 0006-3495</identifier><identifier>EISSN: 1542-0086</identifier><identifier>DOI: 10.1529/biophysj.106.091843</identifier><identifier>PMID: 16920837</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Biophysical Theory and Modeling ; Biophysics ; Computer Simulation ; Fluid dynamics ; Intercellular Junctions - chemistry ; Intercellular Junctions - physiology ; Lipid Bilayers - chemistry ; Lipid Bilayers - metabolism ; Lipids ; Membrane Fluidity - physiology ; Membranes ; Models, Biological ; Models, Chemical ; Models, Molecular ; Proteins ; Surface tension</subject><ispartof>Biophysical journal, 2006-11, Vol.91 (10), p.3600-3606</ispartof><rights>2006 The Biophysical Society</rights><rights>Copyright Biophysical Society Nov 15, 2006</rights><rights>Copyright © 2006, Biophysical Society 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c484t-9146367acbac757b8abe6a43cf431bb256b151b1671a828b31c107dd21fb132c3</citedby><cites>FETCH-LOGICAL-c484t-9146367acbac757b8abe6a43cf431bb256b151b1671a828b31c107dd21fb132c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1630473/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0006349506720720$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,3537,27901,27902,53766,53768,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16920837$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lin, Lawrence C.-L.</creatorcontrib><creatorcontrib>Groves, Jay T.</creatorcontrib><creatorcontrib>Brown, Frank L.H.</creatorcontrib><title>Analysis of Shape, Fluctuations, and Dynamics in Intermembrane Junctions</title><title>Biophysical journal</title><addtitle>Biophys J</addtitle><description>A dynamic-elastic model for weakly adhered intermembrane junctions is presented. Helfrich membrane energetics coupled to hydrodynamic modes of the surrounding solvent reproduce the average shape, fluctuations, and dynamics of these junctions as measured experimentally. Comparison between numerical results and experimental data provides the first direct measure of surface tension in these systems (0.01–0.06
dyn/cm). 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| source | MEDLINE; Cell Press Archives; Elsevier ScienceDirect Journals; PubMed Central; EZB Electronic Journals Library |
| subjects | Biophysical Theory and Modeling Biophysics Computer Simulation Fluid dynamics Intercellular Junctions - chemistry Intercellular Junctions - physiology Lipid Bilayers - chemistry Lipid Bilayers - metabolism Lipids Membrane Fluidity - physiology Membranes Models, Biological Models, Chemical Models, Molecular Proteins Surface tension |
| title | Analysis of Shape, Fluctuations, and Dynamics in Intermembrane Junctions |
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