CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission

C‐terminal‐binding protein/brefeldin A‐ADP ribosylated substrate (CtBP/BARS) plays key roles in development and oncogenesis as a transcription co‐repressor, and in intracellular traffic as a promoter of Golgi membrane fission. Co‐repressor activity is regulated by NAD(H) binding to CtBP/BARS, while...

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Veröffentlicht in:	The EMBO journal 2003-06, Vol.22 (12), p.3122-3130
Hauptverfasser:	Nardini, Marco, Spanò, Stefania, Cericola, Claudia, Pesce, Alessandra, Massaro, Anna, Millo, Enrico, Luini, Alberto, Corda, Daniela, Bolognesi, Martino
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyl Coenzyme A - metabolism acyl-CoA Adenosine diphosphate Amino Acid Sequence Animals Binding Sites brefeldin A Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Cell Membrane - metabolism Crystallography, X-Ray EMBO09 EMBO20 Golgi Apparatus - metabolism Golgi membrane Membranes Models, Molecular Molecular Sequence Data NAD NAD - chemistry NAD - metabolism Peptides - chemistry Peptides - metabolism Protein Binding Protein Folding Protein Structure, Tertiary Rats Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Repressor Proteins - chemistry Repressor Proteins - genetics Repressor Proteins - metabolism Sequence Alignment transcription co-repression Transcription Factors Transcription, Genetic
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