Platelet-Activating Factor Regulates Cadherin-Catenin Adhesion System Expression and β-Catenin Phosphorylation during Kaposi's Sarcoma Cell Motility

In the present study, we evaluated whether motility of Kaposi's sarcoma (KS) cells induced by platelet-activating factor (PAF) is dependent on the regulation of adherens junctions components. The results obtained indicate that PAF dose and time dependently reduced the endogenous expression of t...

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Veröffentlicht in:	The American journal of pathology 2005-05, Vol.166 (5), p.1515-1522
Hauptverfasser:	Boccellino, Mariarosaria, Camussi, Giovanni, Giovane, Alfonso, Ferro, Luigi, Calderaro, Vincenzo, Balestrieri, Ciro, Quagliuolo, Lucio
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha Catenin Antigens, CD beta Catenin Biological and medical sciences Cadherins - metabolism Cell Adhesion - drug effects Cell Line, Tumor Cell Movement - drug effects Cytoskeletal Proteins - metabolism Dermatology Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Original Research Paper Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phosphorylation - drug effects Platelet Activating Factor - pharmacology Sarcoma, Kaposi - metabolism Sarcoma, Kaposi - pathology Sarcoma, Kaposi - physiopathology Tissue Distribution Trans-Activators - metabolism Tumors of the skin and soft tissue. Premalignant lesions Ubiquitin - metabolism
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