The Vascular Endothelial Growth Factor (VEGF) Receptor Flt-1 (VEGFR-1) Modulates Flk-1 (VEGFR-2) Signaling During Blood Vessel Formation

Mice lacking the vascular endothelial growth factor (VEGF) receptor flt-1 (VEGFR-1) die from vascular overgrowth, caused primarily by aberrant endothelial cell division (Kearney JB, Ambler CA, Monaco KA, Johnson N, Rapoport RG, Bautch VL: Vascular endothelial growth factor receptor Flt-1 negatively...

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Veröffentlicht in:	The American journal of pathology 2004-05, Vol.164 (5), p.1531-1535
Hauptverfasser:	Roberts, David M., Kearney, Joseph B., Johnson, Jennifer H., Rosenberg, Michael P., Kumar, Rakesh, Bautch, Victoria L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Differentiation Cells, Cultured Embryo, Mammalian - cytology General aspects Indoles - pharmacology Ligands Medical sciences Mice Mutation Neovascularization, Physiologic Phenotype Phosphorylation Pyrroles - pharmacology Short Communication Signal Transduction Time Factors Tyrosine - chemistry Tyrosine - metabolism Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-1 - physiology Vascular Endothelial Growth Factor Receptor-2 - metabolism
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