Aluminium toxicity during regular haemodialysis
In the west of Scotland the incidence of dialysis encephalopathy has been confined to three geographical areas where the concentration of aluminium in the water supply is greatly increased owing to the addition of aluminium sulphate. Eight patients with encephalopathy who dialysed at home in these a...
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Veröffentlicht in: | BMJ 1978-04, Vol.1 (6120), p.1101-1103 |
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description | In the west of Scotland the incidence of dialysis encephalopathy has been confined to three geographical areas where the concentration of aluminium in the water supply is greatly increased owing to the addition of aluminium sulphate. Eight patients with encephalopathy who dialysed at home in these areas had greatly increased serum aluminium concentrations, and a significant correlation was found between serum aluminium concentrations and the concentrations of aluminium in the water supply. This study provides further evidence that the dialysis encephalopathy syndrome is due to aluminium intoxication, the major source of aluminium being the water supply from which dialysis fluid prepared. |
doi_str_mv | 10.1136/bmj.1.6120.1101 |
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Eight patients with encephalopathy who dialysed at home in these areas had greatly increased serum aluminium concentrations, and a significant correlation was found between serum aluminium concentrations and the concentrations of aluminium in the water supply. This study provides further evidence that the dialysis encephalopathy syndrome is due to aluminium intoxication, the major source of aluminium being the water supply from which dialysis fluid prepared.</description><identifier>ISSN: 0007-1447</identifier><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1468-5833</identifier><identifier>DOI: 10.1136/bmj.1.6120.1101</identifier><identifier>PMID: 638617</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Adult ; Aluminum ; Aluminum - blood ; Aluminum - poisoning ; Brain Diseases - chemically induced ; Brain Diseases - epidemiology ; Dialysis ; Encephalopathies ; Female ; Home hemodialysis ; Humans ; Intoxication ; Male ; Middle Aged ; Osteomalacia ; Renal Dialysis - adverse effects ; Scotland ; Sudden death ; Water pollution ; Water samples ; Water Supply</subject><ispartof>BMJ, 1978-04, Vol.1 (6120), p.1101-1103</ispartof><rights>Copyright 1978 British Medical Journal</rights><rights>Copyright BMJ Publishing Group LTD Apr 29, 1978</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b4561-95f6243ae99c5023b342eb217649ea39f0b323cd1899c5f481c62bbdf7d853573</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/20418785$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/20418785$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,723,776,780,799,881,27901,27902,53766,53768,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/638617$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Elliott, H L</creatorcontrib><creatorcontrib>Dryburgh, F</creatorcontrib><creatorcontrib>Fell, G S</creatorcontrib><creatorcontrib>Sabet, S</creatorcontrib><creatorcontrib>Macdougall, A I</creatorcontrib><title>Aluminium toxicity during regular haemodialysis</title><title>BMJ</title><addtitle>Br Med J</addtitle><description>In the west of Scotland the incidence of dialysis encephalopathy has been confined to three geographical areas where the concentration of aluminium in the water supply is greatly increased owing to the addition of aluminium sulphate. Eight patients with encephalopathy who dialysed at home in these areas had greatly increased serum aluminium concentrations, and a significant correlation was found between serum aluminium concentrations and the concentrations of aluminium in the water supply. This study provides further evidence that the dialysis encephalopathy syndrome is due to aluminium intoxication, the major source of aluminium being the water supply from which dialysis fluid prepared.</description><subject>Adult</subject><subject>Aluminum</subject><subject>Aluminum - blood</subject><subject>Aluminum - poisoning</subject><subject>Brain Diseases - chemically induced</subject><subject>Brain Diseases - epidemiology</subject><subject>Dialysis</subject><subject>Encephalopathies</subject><subject>Female</subject><subject>Home hemodialysis</subject><subject>Humans</subject><subject>Intoxication</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Osteomalacia</subject><subject>Renal Dialysis - adverse effects</subject><subject>Scotland</subject><subject>Sudden death</subject><subject>Water pollution</subject><subject>Water samples</subject><subject>Water Supply</subject><issn>0007-1447</issn><issn>0959-8138</issn><issn>1468-5833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkc1v1DAQxS3E12rpmQtIKyFxQMqux3Zs51KpWpUPUeDA0uvISZytlyQudlJ1_3scpVoBF07W6P1m_GYeIS-BrgG43JTdYQ1rCWyqKTwiCxBSZ7nm_DFZUEpVBkKo5-QsxkMqGVe6kOIZeSq5lqAWZHPRjp3r3ditBn_vKjccV_UYXL9fBbsfWxNWN8Z2vnamPUYXX5AnjWmjPXt4l-TH-8vd9mN29e3Dp-3FVVaKXEJW5I1kghtbFFWevi25YLZkoKQorOFFQ0vOeFWDnoBGaKgkK8u6UbXOea74kpzPc2_HsrN1ZfshmBZvg-tMOKI3Dv9WeneDe3-HIKmYB7x9GBD8r9HGATsXK9u2prd-jAi8YJoLncA3_4AHP4Y-LYeglORUsUIkajNTVfAxBtucrADFKQtMWSDglAVOWaSOV39ucOLnyyf59Swf4uDDSWVUgFbpBkuSzbqLg70_6Sb8RKm4yvHr9Rbz3TXbfdZf8Hvi38385ON_3n4DaTap2g</recordid><startdate>19780429</startdate><enddate>19780429</enddate><creator>Elliott, H L</creator><creator>Dryburgh, F</creator><creator>Fell, G S</creator><creator>Sabet, S</creator><creator>Macdougall, A I</creator><general>British Medical Journal Publishing Group</general><general>British Medical Association</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7QH</scope><scope>5PM</scope></search><sort><creationdate>19780429</creationdate><title>Aluminium toxicity during regular haemodialysis</title><author>Elliott, H L ; Dryburgh, F ; Fell, G S ; Sabet, S ; Macdougall, A I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b4561-95f6243ae99c5023b342eb217649ea39f0b323cd1899c5f481c62bbdf7d853573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Adult</topic><topic>Aluminum</topic><topic>Aluminum - blood</topic><topic>Aluminum - poisoning</topic><topic>Brain Diseases - chemically induced</topic><topic>Brain Diseases - epidemiology</topic><topic>Dialysis</topic><topic>Encephalopathies</topic><topic>Female</topic><topic>Home hemodialysis</topic><topic>Humans</topic><topic>Intoxication</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Osteomalacia</topic><topic>Renal Dialysis - adverse effects</topic><topic>Scotland</topic><topic>Sudden death</topic><topic>Water pollution</topic><topic>Water samples</topic><topic>Water Supply</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Elliott, H L</creatorcontrib><creatorcontrib>Dryburgh, F</creatorcontrib><creatorcontrib>Fell, G S</creatorcontrib><creatorcontrib>Sabet, S</creatorcontrib><creatorcontrib>Macdougall, A I</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Aqualine</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Elliott, H L</au><au>Dryburgh, F</au><au>Fell, G S</au><au>Sabet, S</au><au>Macdougall, A I</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aluminium toxicity during regular haemodialysis</atitle><jtitle>BMJ</jtitle><addtitle>Br Med J</addtitle><date>1978-04-29</date><risdate>1978</risdate><volume>1</volume><issue>6120</issue><spage>1101</spage><epage>1103</epage><pages>1101-1103</pages><issn>0007-1447</issn><issn>0959-8138</issn><eissn>1468-5833</eissn><abstract>In the west of Scotland the incidence of dialysis encephalopathy has been confined to three geographical areas where the concentration of aluminium in the water supply is greatly increased owing to the addition of aluminium sulphate. Eight patients with encephalopathy who dialysed at home in these areas had greatly increased serum aluminium concentrations, and a significant correlation was found between serum aluminium concentrations and the concentrations of aluminium in the water supply. This study provides further evidence that the dialysis encephalopathy syndrome is due to aluminium intoxication, the major source of aluminium being the water supply from which dialysis fluid prepared.</abstract><cop>England</cop><pub>British Medical Journal Publishing Group</pub><pmid>638617</pmid><doi>10.1136/bmj.1.6120.1101</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aluminum Aluminum - blood Aluminum - poisoning Brain Diseases - chemically induced Brain Diseases - epidemiology Dialysis Encephalopathies Female Home hemodialysis Humans Intoxication Male Middle Aged Osteomalacia Renal Dialysis - adverse effects Scotland Sudden death Water pollution Water samples Water Supply |
title | Aluminium toxicity during regular haemodialysis |
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