Analysis of Interleukin-27 (EBI3/p28) Expression in Epstein-Barr Virus- and Human T-Cell Leukemia Virus Type 1-Associated Lymphomas: Heterogeneous Expression of EBI3 Subunit by Tumoral Cells

Interleukin (IL)-27 is a novel heterodimeric cytokine of the IL-12 family that is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) and p28. EBI3 is expressed at high levels in EBV-transformed B-cell lines and is induced in vitro by the EBV oncogene LMP1 in a nuclear factor (N...

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Veröffentlicht in:	The American journal of pathology 2005-04, Vol.166 (4), p.1217-1228
Hauptverfasser:	Larousserie, Frederique, Bardel, Emilie, Pflanz, Stefan, Arnulf, Bertrand, Lome-Maldonado, Carmen, Hermine, Olivier, Bregeaud, Laurence, Perennec, Monique, Brousse, Nicole, Kastelein, Rob, Devergne, Odile
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Deltaretrovirus - metabolism Enzyme-Linked Immunosorbent Assay Epstein-Barr Virus Infections - metabolism Flow Cytometry Hematologic and hematopoietic diseases Herpesvirus 4, Human - metabolism Humans Immunohistochemistry In Situ Hybridization Interleukins - biosynthesis Investigative techniques, diagnostic techniques (general aspects) Jurkat Cells Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma - metabolism Lymphoma - virology Medical sciences NF-kappa B - metabolism Original Research Paper Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Tumor Virus Infections - metabolism
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