Capsule Structure Changes Associated with Cryptococcus neoformans Crossing of the Blood-Brain Barrier

Cryptococcus neoformans is a yeast responsible for disseminated meningoencephalitis in patients with cellular immune defects. The major virulence factor is the polysaccharide capsule. We took advantage of a relevant murine model of disseminated meningoencephalitis to study the early events associate...

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Veröffentlicht in:	The American journal of pathology 2005-02, Vol.166 (2), p.421-432
Hauptverfasser:	Charlier, Caroline, Chrétien, Fabrice, Baudrimont, Marielle, Mordelet, Elodie, Lortholary, Olivier, Dromer, Françoise
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood-Brain Barrier Brain - microbiology Brain - pathology Collagen - chemistry Cryptococcus neoformans - metabolism Investigative techniques, diagnostic techniques (general aspects) Kinetics Male Medical sciences Meningitis, Cryptococcal - microbiology Meningitis, Cryptococcal - pathology Meningoencephalitis - microbiology Meningoencephalitis - pathology Mice Microcirculation - microbiology Microcirculation - pathology Microscopy, Electron Microscopy, Fluorescence Original Research Paper Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Phenotype Time Factors Tissue Distribution
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