Influence of Amniotic Fluid Volume on Lecithin Estimation in Prediction of Respiratory Distress
One hundred samples of amniotic fluid were obtained by amniocentesis from 82 patients at different stages of normal and abnormal pregnancies. The concentration of lecithin was estimated together with the volume of the amniotic fluid, using the dilution technique. Thus the total quantity of lecithin...
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| Veröffentlicht in: | BMJ 1973-06, Vol.2 (5868), p.689-691 |
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| creator | Falconer, G. F. Hodge, J. S. Gadd, R. L. |
| description | One hundred samples of amniotic fluid were obtained by amniocentesis from 82 patients at different stages of normal and abnormal pregnancies. The concentration of lecithin was estimated together with the volume of the amniotic fluid, using the dilution technique. Thus the total quantity of lecithin in any amniotic sac could be calculated. While confirming the findings of others that concentrations of lecithin below 3·5 mg/100 ml in the liquor immediately before delivery suggested that the baby was likely to develop respiratory distress syndrome, we found that in borderline cases the total amount of lecithin in the sac was of greater prognostic significance than the lecithin concentration. |
| doi_str_mv | 10.1136/bmj.2.5868.689 |
| format | Article |
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While confirming the findings of others that concentrations of lecithin below 3·5 mg/100 ml in the liquor immediately before delivery suggested that the baby was likely to develop respiratory distress syndrome, we found that in borderline cases the total amount of lecithin in the sac was of greater prognostic significance than the lecithin concentration.</description><identifier>ISSN: 0007-1447</identifier><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1468-5833</identifier><identifier>DOI: 10.1136/bmj.2.5868.689</identifier><identifier>PMID: 4741055</identifier><language>eng</language><publisher>England: British Medical Journal Publishing Group</publisher><subject>Amniocentesis ; Amniotic fluid ; Amniotic Fluid - analysis ; Biochemistry ; Cesarean section ; Estimation methods ; Female ; Gynecology ; Humans ; Infant, Newborn ; Medical specialists ; Obstetric Labor Complications ; Obstetrics ; Papers and Originals ; Phosphatidylcholines ; Phosphatidylcholines - analysis ; Pregnancy ; Prognosis ; Respiratory distress ; Respiratory Distress Syndrome, Newborn - diagnosis</subject><ispartof>BMJ, 1973-06, Vol.2 (5868), p.689-691</ispartof><rights>Copyright 1973 British Medical Journal</rights><rights>Copyright BMJ Publishing Group LTD Jun 23, 1973</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b507t-29500b0a488ed9af03a7ff452ee5eb15223d354cf20a94880e602dd22676de073</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/25420422$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/25420422$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,723,776,780,799,881,27903,27904,53770,53772,57996,58229</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4741055$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Falconer, G. F.</creatorcontrib><creatorcontrib>Hodge, J. S.</creatorcontrib><creatorcontrib>Gadd, R. L.</creatorcontrib><title>Influence of Amniotic Fluid Volume on Lecithin Estimation in Prediction of Respiratory Distress</title><title>BMJ</title><addtitle>Br Med J</addtitle><description>One hundred samples of amniotic fluid were obtained by amniocentesis from 82 patients at different stages of normal and abnormal pregnancies. The concentration of lecithin was estimated together with the volume of the amniotic fluid, using the dilution technique. Thus the total quantity of lecithin in any amniotic sac could be calculated. While confirming the findings of others that concentrations of lecithin below 3·5 mg/100 ml in the liquor immediately before delivery suggested that the baby was likely to develop respiratory distress syndrome, we found that in borderline cases the total amount of lecithin in the sac was of greater prognostic significance than the lecithin concentration.</description><subject>Amniocentesis</subject><subject>Amniotic fluid</subject><subject>Amniotic Fluid - analysis</subject><subject>Biochemistry</subject><subject>Cesarean section</subject><subject>Estimation methods</subject><subject>Female</subject><subject>Gynecology</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Medical specialists</subject><subject>Obstetric Labor Complications</subject><subject>Obstetrics</subject><subject>Papers and Originals</subject><subject>Phosphatidylcholines</subject><subject>Phosphatidylcholines - analysis</subject><subject>Pregnancy</subject><subject>Prognosis</subject><subject>Respiratory distress</subject><subject>Respiratory Distress Syndrome, Newborn - diagnosis</subject><issn>0007-1447</issn><issn>0959-8138</issn><issn>1468-5833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkc1v1DAQxS0EKqvSKzekSEhIHBLGjr9yQWqXthStACHYq-VNJtRLEm_tBNH_HoddLR8XTtb4_Wb0Zh4hTykUlJby1abfFqwQWupC6uoBWVAudS50WT4kCwBQOeVcPSZnMW5TyUqlK8lPyAlXnIIQC2JuhrabcKgx82123g_Oj67OrrrJNdnad1OfhCFbYe3GWzdkl3F0vR1d-kvVx4CNq39VqfsTxp0LdvThPnvj4hgwxifkUWu7iGeH95R8ubr8vHybrz5c3yzPV_lGgBpzVgmADViuNTaVbaG0qm25YIgCN1QwVjal4HXLwFYJApTAmoYxqWSDoMpT8no_dzdtemxqHMZgO7MLyW24N94687cyuFvz1X83VOhKCZYGvDgMCP5uwjia3sUau84O6KdoNAOmgFcJfP4PuPVTGNJyhiolqZZSz36KPVUHH2PA9miFgpmzMyk7w8ycnUnZpYZnfy5wxA9J_da3MR34KDPBGXA2-8_3ejo8_jjqNnwzUpVKmPfrpVkK8Q4uLtbmOvEv9_zs4z_efgJONbsv</recordid><startdate>19730623</startdate><enddate>19730623</enddate><creator>Falconer, G. 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F. ; Hodge, J. S. ; Gadd, R. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b507t-29500b0a488ed9af03a7ff452ee5eb15223d354cf20a94880e602dd22676de073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Amniocentesis</topic><topic>Amniotic fluid</topic><topic>Amniotic Fluid - analysis</topic><topic>Biochemistry</topic><topic>Cesarean section</topic><topic>Estimation methods</topic><topic>Female</topic><topic>Gynecology</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Medical specialists</topic><topic>Obstetric Labor Complications</topic><topic>Obstetrics</topic><topic>Papers and Originals</topic><topic>Phosphatidylcholines</topic><topic>Phosphatidylcholines - analysis</topic><topic>Pregnancy</topic><topic>Prognosis</topic><topic>Respiratory distress</topic><topic>Respiratory Distress Syndrome, Newborn - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Falconer, G. 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F.</au><au>Hodge, J. S.</au><au>Gadd, R. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Amniotic Fluid Volume on Lecithin Estimation in Prediction of Respiratory Distress</atitle><jtitle>BMJ</jtitle><addtitle>Br Med J</addtitle><date>1973-06-23</date><risdate>1973</risdate><volume>2</volume><issue>5868</issue><spage>689</spage><epage>691</epage><pages>689-691</pages><issn>0007-1447</issn><issn>0959-8138</issn><eissn>1468-5833</eissn><abstract>One hundred samples of amniotic fluid were obtained by amniocentesis from 82 patients at different stages of normal and abnormal pregnancies. The concentration of lecithin was estimated together with the volume of the amniotic fluid, using the dilution technique. Thus the total quantity of lecithin in any amniotic sac could be calculated. While confirming the findings of others that concentrations of lecithin below 3·5 mg/100 ml in the liquor immediately before delivery suggested that the baby was likely to develop respiratory distress syndrome, we found that in borderline cases the total amount of lecithin in the sac was of greater prognostic significance than the lecithin concentration.</abstract><cop>England</cop><pub>British Medical Journal Publishing Group</pub><pmid>4741055</pmid><doi>10.1136/bmj.2.5868.689</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Jstor Complete Legacy; PubMed Central |
| subjects | Amniocentesis Amniotic fluid Amniotic Fluid - analysis Biochemistry Cesarean section Estimation methods Female Gynecology Humans Infant, Newborn Medical specialists Obstetric Labor Complications Obstetrics Papers and Originals Phosphatidylcholines Phosphatidylcholines - analysis Pregnancy Prognosis Respiratory distress Respiratory Distress Syndrome, Newborn - diagnosis |
| title | Influence of Amniotic Fluid Volume on Lecithin Estimation in Prediction of Respiratory Distress |
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