Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis
Using a beta-glucuronidase (GUS) reporter-COP1 fusion transgene, it was shown previously that Arabidopsis COP1 acts within the nucleus as a repressor of seedling photomorphogenic development and that light inactivation of COP1 was accompanied by a reduction of COP1 nuclear abundance (A.G. von Arnim,...
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| Veröffentlicht in: | Plant physiology (Bethesda) 1997-07, Vol.114 (3), p.779-788 |
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| creator | Von Arnim, A.G Osterlund, M.T Kwok, S.F Deng, X.W |
| description | Using a beta-glucuronidase (GUS) reporter-COP1 fusion transgene, it was shown previously that Arabidopsis COP1 acts within the nucleus as a repressor of seedling photomorphogenic development and that light inactivation of COP1 was accompanied by a reduction of COP1 nuclear abundance (A.G. von Arnim, X.-W. Deng [1994] Cell 79: 1035-1045). Here we report that the GUS-COP1 fusion transgene can completely rescue the defect of cop1 mutations and thus is fully functional during seedling development. The kinetics of GUS-COP1 relocalization in a cop1 null mutant background during dark/light transitions imply that the regulation of the functional nuclear COP1 level plays a role in stably maintaining a committed seedling's developmental fate rather than in causing such a commitment. Analysis of GUS-COP1 cellular localization in mutant hypocotyls of all other pleiotropic COP/DET/FUS loci revealed that nuclear localization of GUS-COP1 was diminished under both dark and light conditions in all mutants tested, whereas nuclear localization was not affected in the less pleiotropic cop4 mutant. Using both the brassinosteroid-deficient mutant det2 and brassinosteroid treatment of wild-type seedlings, we have demonstrated that brassinosteroid does not control the hypocotyl cell elongation through regulating nuclear localization of COP1. The growth regulator cytokinin, which also dramatically reduced hypocotyl cell elongation in the absence of light, did not prevent GUS-COP1 nuclear localization in dark-grown seedlings. Our results suggest that all of the previously characterized pleiotropic COP/DET/FUS loci are required for the proper nuclear localization of the COP1 protein in the dark, whereas the less pleiotropic COP/DET loci or plant regulators tested are likely to act either downstream of COP1 or by independent pathways |
| doi_str_mv | 10.1104/pp.114.3.779 |
| format | Article |
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Deng [1994] Cell 79: 1035-1045). Here we report that the GUS-COP1 fusion transgene can completely rescue the defect of cop1 mutations and thus is fully functional during seedling development. The kinetics of GUS-COP1 relocalization in a cop1 null mutant background during dark/light transitions imply that the regulation of the functional nuclear COP1 level plays a role in stably maintaining a committed seedling's developmental fate rather than in causing such a commitment. Analysis of GUS-COP1 cellular localization in mutant hypocotyls of all other pleiotropic COP/DET/FUS loci revealed that nuclear localization of GUS-COP1 was diminished under both dark and light conditions in all mutants tested, whereas nuclear localization was not affected in the less pleiotropic cop4 mutant. Using both the brassinosteroid-deficient mutant det2 and brassinosteroid treatment of wild-type seedlings, we have demonstrated that brassinosteroid does not control the hypocotyl cell elongation through regulating nuclear localization of COP1. The growth regulator cytokinin, which also dramatically reduced hypocotyl cell elongation in the absence of light, did not prevent GUS-COP1 nuclear localization in dark-grown seedlings. Our results suggest that all of the previously characterized pleiotropic COP/DET/FUS loci are required for the proper nuclear localization of the COP1 protein in the dark, whereas the less pleiotropic COP/DET loci or plant regulators tested are likely to act either downstream of COP1 or by independent pathways</description><identifier>ISSN: 0032-0889</identifier><identifier>EISSN: 1532-2548</identifier><identifier>DOI: 10.1104/pp.114.3.779</identifier><identifier>PMID: 9232869</identifier><identifier>CODEN: PPHYA5</identifier><language>eng</language><publisher>Rockville, MD: American Society of Plant Physiologists</publisher><subject>ACTIVIDAD ENZIMATICA ; ACTIVITE ENZYMATIQUE ; Arabidopsis - genetics ; Arabidopsis - physiology ; Arabidopsis Proteins ; ARABIDOPSIS THALIANA ; BETA-GLUCURONIDASE ; Biological and medical sciences ; BRASINOSTEROIDES ; BRASSINOSTEROIDE ; BRASSINOSTEROIDS ; Carrier Proteins - biosynthesis ; Carrier Proteins - genetics ; Cell Biology and Signal Transduction ; Cell growth ; Cell nucleus ; Cell Nucleus - metabolism ; CELLS ; CELLULE ; CELULAS ; CITOQUININAS ; CRECIMIENTO ; CROISSANCE ; Crosses, Genetic ; CYTOKININE ; CYTOKININS ; DARKNESS ; Developmental biology ; ENZYMIC ACTIVITY ; EXPRESION GENICA ; EXPRESSION DES GENES ; Fundamental and applied biological sciences. Psychology ; GENE ; GENE EXPRESSION ; Gene Expression Regulation, Developmental ; GENES ; Genetic mutation ; GENETIC REGULATION ; GENETIC VARIATION ; GENETICA ; GENETICS ; GENETIQUE ; GLICOSIDASAS ; Glucuronidase - biosynthesis ; GLYCOSIDASE ; GLYCOSIDASES ; GROWTH ; HIPOCOTILOS ; Hypocotyl ; HYPOCOTYLE ; HYPOCOTYLS ; LIGHT ; LOCALIZATION ; LOCI ; LOCUS ; LUMIERE ; LUZ ; MORFOGENESIS ; MORPHOGENESE ; MORPHOGENESIS ; Morphogenesis - physiology ; Morphogenesis - radiation effects ; MUTACION ; Mutagenesis ; MUTANT ; MUTANTES ; MUTANTS ; MUTATION ; NOYAU CELLULAIRE ; NUCLEI ; NUCLEO ; NUCLEUS ; OBSCURIDAD ; OBSCURITE ; Phenotype ; Phenotypes ; Physical agents ; Plant cells ; Plant Growth Regulators - physiology ; Plant physiology and development ; Plant Proteins - biosynthesis ; Plant Proteins - genetics ; Plants, Genetically Modified ; PLANTULAS ; PLANTULE ; Recombinant Fusion Proteins ; Recombination, Genetic ; REPORTER GENES ; Repressor Proteins - biosynthesis ; Repressor Proteins - genetics ; SEEDLINGS ; Transgenes ; Ubiquitin-Protein Ligases ; VARIACION GENETICA ; VARIATION GENETIQUE ; Vegetative apparatus, growth and morphogenesis. Senescence ; WILD STRAINS</subject><ispartof>Plant physiology (Bethesda), 1997-07, Vol.114 (3), p.779-788</ispartof><rights>Copyright 1997 American Society of Plant Physiologists</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c517t-88ad7ae327fe2992d1ce2e1505754f849613c0a5b00c57b116e5ec0141cda9ed3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4277769$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4277769$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,314,780,784,803,885,27924,27925,58017,58250</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2748629$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9232869$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Von Arnim, A.G</creatorcontrib><creatorcontrib>Osterlund, M.T</creatorcontrib><creatorcontrib>Kwok, S.F</creatorcontrib><creatorcontrib>Deng, X.W</creatorcontrib><title>Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis</title><title>Plant physiology (Bethesda)</title><addtitle>Plant Physiol</addtitle><description>Using a beta-glucuronidase (GUS) reporter-COP1 fusion transgene, it was shown previously that Arabidopsis COP1 acts within the nucleus as a repressor of seedling photomorphogenic development and that light inactivation of COP1 was accompanied by a reduction of COP1 nuclear abundance (A.G. von Arnim, X.-W. Deng [1994] Cell 79: 1035-1045). Here we report that the GUS-COP1 fusion transgene can completely rescue the defect of cop1 mutations and thus is fully functional during seedling development. The kinetics of GUS-COP1 relocalization in a cop1 null mutant background during dark/light transitions imply that the regulation of the functional nuclear COP1 level plays a role in stably maintaining a committed seedling's developmental fate rather than in causing such a commitment. Analysis of GUS-COP1 cellular localization in mutant hypocotyls of all other pleiotropic COP/DET/FUS loci revealed that nuclear localization of GUS-COP1 was diminished under both dark and light conditions in all mutants tested, whereas nuclear localization was not affected in the less pleiotropic cop4 mutant. Using both the brassinosteroid-deficient mutant det2 and brassinosteroid treatment of wild-type seedlings, we have demonstrated that brassinosteroid does not control the hypocotyl cell elongation through regulating nuclear localization of COP1. The growth regulator cytokinin, which also dramatically reduced hypocotyl cell elongation in the absence of light, did not prevent GUS-COP1 nuclear localization in dark-grown seedlings. Our results suggest that all of the previously characterized pleiotropic COP/DET/FUS loci are required for the proper nuclear localization of the COP1 protein in the dark, whereas the less pleiotropic COP/DET loci or plant regulators tested are likely to act either downstream of COP1 or by independent pathways</description><subject>ACTIVIDAD ENZIMATICA</subject><subject>ACTIVITE ENZYMATIQUE</subject><subject>Arabidopsis - genetics</subject><subject>Arabidopsis - physiology</subject><subject>Arabidopsis Proteins</subject><subject>ARABIDOPSIS THALIANA</subject><subject>BETA-GLUCURONIDASE</subject><subject>Biological and medical sciences</subject><subject>BRASINOSTEROIDES</subject><subject>BRASSINOSTEROIDE</subject><subject>BRASSINOSTEROIDS</subject><subject>Carrier Proteins - biosynthesis</subject><subject>Carrier Proteins - genetics</subject><subject>Cell Biology and Signal Transduction</subject><subject>Cell growth</subject><subject>Cell nucleus</subject><subject>Cell Nucleus - metabolism</subject><subject>CELLS</subject><subject>CELLULE</subject><subject>CELULAS</subject><subject>CITOQUININAS</subject><subject>CRECIMIENTO</subject><subject>CROISSANCE</subject><subject>Crosses, Genetic</subject><subject>CYTOKININE</subject><subject>CYTOKININS</subject><subject>DARKNESS</subject><subject>Developmental biology</subject><subject>ENZYMIC ACTIVITY</subject><subject>EXPRESION GENICA</subject><subject>EXPRESSION DES GENES</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>GENE</subject><subject>GENE EXPRESSION</subject><subject>Gene Expression Regulation, Developmental</subject><subject>GENES</subject><subject>Genetic mutation</subject><subject>GENETIC REGULATION</subject><subject>GENETIC VARIATION</subject><subject>GENETICA</subject><subject>GENETICS</subject><subject>GENETIQUE</subject><subject>GLICOSIDASAS</subject><subject>Glucuronidase - biosynthesis</subject><subject>GLYCOSIDASE</subject><subject>GLYCOSIDASES</subject><subject>GROWTH</subject><subject>HIPOCOTILOS</subject><subject>Hypocotyl</subject><subject>HYPOCOTYLE</subject><subject>HYPOCOTYLS</subject><subject>LIGHT</subject><subject>LOCALIZATION</subject><subject>LOCI</subject><subject>LOCUS</subject><subject>LUMIERE</subject><subject>LUZ</subject><subject>MORFOGENESIS</subject><subject>MORPHOGENESE</subject><subject>MORPHOGENESIS</subject><subject>Morphogenesis - physiology</subject><subject>Morphogenesis - radiation effects</subject><subject>MUTACION</subject><subject>Mutagenesis</subject><subject>MUTANT</subject><subject>MUTANTES</subject><subject>MUTANTS</subject><subject>MUTATION</subject><subject>NOYAU CELLULAIRE</subject><subject>NUCLEI</subject><subject>NUCLEO</subject><subject>NUCLEUS</subject><subject>OBSCURIDAD</subject><subject>OBSCURITE</subject><subject>Phenotype</subject><subject>Phenotypes</subject><subject>Physical agents</subject><subject>Plant cells</subject><subject>Plant Growth Regulators - physiology</subject><subject>Plant physiology and development</subject><subject>Plant Proteins - biosynthesis</subject><subject>Plant Proteins - genetics</subject><subject>Plants, Genetically Modified</subject><subject>PLANTULAS</subject><subject>PLANTULE</subject><subject>Recombinant Fusion Proteins</subject><subject>Recombination, Genetic</subject><subject>REPORTER GENES</subject><subject>Repressor Proteins - biosynthesis</subject><subject>Repressor Proteins - genetics</subject><subject>SEEDLINGS</subject><subject>Transgenes</subject><subject>Ubiquitin-Protein Ligases</subject><subject>VARIACION GENETICA</subject><subject>VARIATION GENETIQUE</subject><subject>Vegetative apparatus, growth and morphogenesis. Senescence</subject><subject>WILD STRAINS</subject><issn>0032-0889</issn><issn>1532-2548</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU1v1DAQhiMEKqVw4whSDohTd_E4duwceqhWUJAqFQl6tmadydaVExs7qcS_x6tdrcrpted95ktTVe-BrQGY-BJjUbFu1kp1L6pzkA1fcSn0y-qcsfJmWnevqzc5PzLGoAFxVp11vOG67c6rfEMTzc7WOPV1T0_kQxxpmtHXNkxzCr4OQz0t1hOmGq1dxsXj7MK0j2_ufsJljXWimCjnkPbB-BDmMIZUdFeKZ5drN9XXCbeuD7F831avBvSZ3h31orr_9vX35vvq9u7mx-b6dmUlqHmlNfYKqeFqIN51vAdLnEAyqaQYtOhaaCxDuWXMSrUFaEmSZSDA9thR31xUV4e6cdmO1NuyVkJvYnIjpr8moDP_O5N7MLvwZEDqphUl__MxP4U_C-XZjC5b8h4nCks20HINUqkCXh5Am0LOiYZTD2BmfyMTY1FhGlNuVPCPz-c6wcejFP_T0cds0Q8JJ-vyCeNK6JbvsQ8H7DHPIZ1swZVS7bMuAwaDu1Qq3P-CrlOsBV6m-AcpFq7C</recordid><startdate>19970701</startdate><enddate>19970701</enddate><creator>Von Arnim, A.G</creator><creator>Osterlund, M.T</creator><creator>Kwok, S.F</creator><creator>Deng, X.W</creator><general>American Society of Plant Physiologists</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>5PM</scope></search><sort><creationdate>19970701</creationdate><title>Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis</title><author>Von Arnim, A.G ; Osterlund, M.T ; Kwok, S.F ; Deng, X.W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c517t-88ad7ae327fe2992d1ce2e1505754f849613c0a5b00c57b116e5ec0141cda9ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>ACTIVIDAD ENZIMATICA</topic><topic>ACTIVITE ENZYMATIQUE</topic><topic>Arabidopsis - genetics</topic><topic>Arabidopsis - physiology</topic><topic>Arabidopsis Proteins</topic><topic>ARABIDOPSIS THALIANA</topic><topic>BETA-GLUCURONIDASE</topic><topic>Biological and medical sciences</topic><topic>BRASINOSTEROIDES</topic><topic>BRASSINOSTEROIDE</topic><topic>BRASSINOSTEROIDS</topic><topic>Carrier Proteins - biosynthesis</topic><topic>Carrier Proteins - genetics</topic><topic>Cell Biology and Signal Transduction</topic><topic>Cell growth</topic><topic>Cell nucleus</topic><topic>Cell Nucleus - metabolism</topic><topic>CELLS</topic><topic>CELLULE</topic><topic>CELULAS</topic><topic>CITOQUININAS</topic><topic>CRECIMIENTO</topic><topic>CROISSANCE</topic><topic>Crosses, Genetic</topic><topic>CYTOKININE</topic><topic>CYTOKININS</topic><topic>DARKNESS</topic><topic>Developmental biology</topic><topic>ENZYMIC ACTIVITY</topic><topic>EXPRESION GENICA</topic><topic>EXPRESSION DES GENES</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>GENE</topic><topic>GENE EXPRESSION</topic><topic>Gene Expression Regulation, Developmental</topic><topic>GENES</topic><topic>Genetic mutation</topic><topic>GENETIC REGULATION</topic><topic>GENETIC VARIATION</topic><topic>GENETICA</topic><topic>GENETICS</topic><topic>GENETIQUE</topic><topic>GLICOSIDASAS</topic><topic>Glucuronidase - biosynthesis</topic><topic>GLYCOSIDASE</topic><topic>GLYCOSIDASES</topic><topic>GROWTH</topic><topic>HIPOCOTILOS</topic><topic>Hypocotyl</topic><topic>HYPOCOTYLE</topic><topic>HYPOCOTYLS</topic><topic>LIGHT</topic><topic>LOCALIZATION</topic><topic>LOCI</topic><topic>LOCUS</topic><topic>LUMIERE</topic><topic>LUZ</topic><topic>MORFOGENESIS</topic><topic>MORPHOGENESE</topic><topic>MORPHOGENESIS</topic><topic>Morphogenesis - physiology</topic><topic>Morphogenesis - radiation effects</topic><topic>MUTACION</topic><topic>Mutagenesis</topic><topic>MUTANT</topic><topic>MUTANTES</topic><topic>MUTANTS</topic><topic>MUTATION</topic><topic>NOYAU CELLULAIRE</topic><topic>NUCLEI</topic><topic>NUCLEO</topic><topic>NUCLEUS</topic><topic>OBSCURIDAD</topic><topic>OBSCURITE</topic><topic>Phenotype</topic><topic>Phenotypes</topic><topic>Physical agents</topic><topic>Plant cells</topic><topic>Plant Growth Regulators - physiology</topic><topic>Plant physiology and development</topic><topic>Plant Proteins - biosynthesis</topic><topic>Plant Proteins - genetics</topic><topic>Plants, Genetically Modified</topic><topic>PLANTULAS</topic><topic>PLANTULE</topic><topic>Recombinant Fusion Proteins</topic><topic>Recombination, Genetic</topic><topic>REPORTER GENES</topic><topic>Repressor Proteins - biosynthesis</topic><topic>Repressor Proteins - genetics</topic><topic>SEEDLINGS</topic><topic>Transgenes</topic><topic>Ubiquitin-Protein Ligases</topic><topic>VARIACION GENETICA</topic><topic>VARIATION GENETIQUE</topic><topic>Vegetative apparatus, growth and morphogenesis. Senescence</topic><topic>WILD STRAINS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Von Arnim, A.G</creatorcontrib><creatorcontrib>Osterlund, M.T</creatorcontrib><creatorcontrib>Kwok, S.F</creatorcontrib><creatorcontrib>Deng, X.W</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Plant physiology (Bethesda)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Von Arnim, A.G</au><au>Osterlund, M.T</au><au>Kwok, S.F</au><au>Deng, X.W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis</atitle><jtitle>Plant physiology (Bethesda)</jtitle><addtitle>Plant Physiol</addtitle><date>1997-07-01</date><risdate>1997</risdate><volume>114</volume><issue>3</issue><spage>779</spage><epage>788</epage><pages>779-788</pages><issn>0032-0889</issn><eissn>1532-2548</eissn><coden>PPHYA5</coden><abstract>Using a beta-glucuronidase (GUS) reporter-COP1 fusion transgene, it was shown previously that Arabidopsis COP1 acts within the nucleus as a repressor of seedling photomorphogenic development and that light inactivation of COP1 was accompanied by a reduction of COP1 nuclear abundance (A.G. von Arnim, X.-W. Deng [1994] Cell 79: 1035-1045). Here we report that the GUS-COP1 fusion transgene can completely rescue the defect of cop1 mutations and thus is fully functional during seedling development. The kinetics of GUS-COP1 relocalization in a cop1 null mutant background during dark/light transitions imply that the regulation of the functional nuclear COP1 level plays a role in stably maintaining a committed seedling's developmental fate rather than in causing such a commitment. Analysis of GUS-COP1 cellular localization in mutant hypocotyls of all other pleiotropic COP/DET/FUS loci revealed that nuclear localization of GUS-COP1 was diminished under both dark and light conditions in all mutants tested, whereas nuclear localization was not affected in the less pleiotropic cop4 mutant. Using both the brassinosteroid-deficient mutant det2 and brassinosteroid treatment of wild-type seedlings, we have demonstrated that brassinosteroid does not control the hypocotyl cell elongation through regulating nuclear localization of COP1. The growth regulator cytokinin, which also dramatically reduced hypocotyl cell elongation in the absence of light, did not prevent GUS-COP1 nuclear localization in dark-grown seedlings. Our results suggest that all of the previously characterized pleiotropic COP/DET/FUS loci are required for the proper nuclear localization of the COP1 protein in the dark, whereas the less pleiotropic COP/DET loci or plant regulators tested are likely to act either downstream of COP1 or by independent pathways</abstract><cop>Rockville, MD</cop><pub>American Society of Plant Physiologists</pub><pmid>9232869</pmid><doi>10.1104/pp.114.3.779</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Plant physiology (Bethesda), 1997-07, Vol.114 (3), p.779-788 |
| issn | 0032-0889 1532-2548 |
| language | eng |
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| source | MEDLINE; JSTOR Archive Collection A-Z Listing; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | ACTIVIDAD ENZIMATICA ACTIVITE ENZYMATIQUE Arabidopsis - genetics Arabidopsis - physiology Arabidopsis Proteins ARABIDOPSIS THALIANA BETA-GLUCURONIDASE Biological and medical sciences BRASINOSTEROIDES BRASSINOSTEROIDE BRASSINOSTEROIDS Carrier Proteins - biosynthesis Carrier Proteins - genetics Cell Biology and Signal Transduction Cell growth Cell nucleus Cell Nucleus - metabolism CELLS CELLULE CELULAS CITOQUININAS CRECIMIENTO CROISSANCE Crosses, Genetic CYTOKININE CYTOKININS DARKNESS Developmental biology ENZYMIC ACTIVITY EXPRESION GENICA EXPRESSION DES GENES Fundamental and applied biological sciences. Psychology GENE GENE EXPRESSION Gene Expression Regulation, Developmental GENES Genetic mutation GENETIC REGULATION GENETIC VARIATION GENETICA GENETICS GENETIQUE GLICOSIDASAS Glucuronidase - biosynthesis GLYCOSIDASE GLYCOSIDASES GROWTH HIPOCOTILOS Hypocotyl HYPOCOTYLE HYPOCOTYLS LIGHT LOCALIZATION LOCI LOCUS LUMIERE LUZ MORFOGENESIS MORPHOGENESE MORPHOGENESIS Morphogenesis - physiology Morphogenesis - radiation effects MUTACION Mutagenesis MUTANT MUTANTES MUTANTS MUTATION NOYAU CELLULAIRE NUCLEI NUCLEO NUCLEUS OBSCURIDAD OBSCURITE Phenotype Phenotypes Physical agents Plant cells Plant Growth Regulators - physiology Plant physiology and development Plant Proteins - biosynthesis Plant Proteins - genetics Plants, Genetically Modified PLANTULAS PLANTULE Recombinant Fusion Proteins Recombination, Genetic REPORTER GENES Repressor Proteins - biosynthesis Repressor Proteins - genetics SEEDLINGS Transgenes Ubiquitin-Protein Ligases VARIACION GENETICA VARIATION GENETIQUE Vegetative apparatus, growth and morphogenesis. Senescence WILD STRAINS |
| title | Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis |
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