7-Dehydrobrefeldin A, a naturally occurring brefeldin A derivative, inhibits secretion and causes a cis-to-trans breakdown of Golgi stacks in plant cells

7-Dehydrobrefeldin A (7-oxo-BFA) is a brefeldin A (BFA) analog that, like BFA, is a potent phytotoxin of Alternaria carthami, a fungal pathogen of safflower (Carthamus tinctorius L.) plants. Both BFA and 7-oxo-BFA have been shown to be causal agents of the leaf spot disease of these plants. We have...

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Veröffentlicht in:	Plant physiology (Bethesda) 1997-02, Vol.113 (2), p.487-492
Hauptverfasser:	Driouich, A. (Universite de Rouen, Mont Saint Aignan, France.), Jauneau, A, Staehelin, L.A
Format:	Artikel
Sprache:	eng
Schlagworte:	ACER PSEUDOPLATANUS ACTIVIDAD ENZIMATICA ACTIVITE ENZYMATIQUE AGENT PATHOGENE ALTERNARIA APARATO GOLGI APPAREIL DE GOLGI BACILLUS SUBTILIS Biological and medical sciences BIOSINTESIS BIOSYNTHESE Brefeldin A CARTHAMUS TINCTORIUS Cell biochemistry Cell Biology and Signal Transduction Cell growth Cell physiology Cells Cells, Cultured Chemical suspensions CULTIVO DE CELULAS CULTURE DE CELLULE Cultured cells Cyclopentanes - pharmacology DOSAGE BIOLOGIQUE ENFERMEDADES FUNGOSAS ENSAYO BIOLOGICO ESTERASAS ESTERASE ESTRUCTURA CELULAR Eukaryotic Cells - drug effects FITOTOXICIDAD FITOTOXINAS Fundamental and applied biological sciences. Psychology Golgi apparatus Golgi Apparatus - drug effects Golgi Apparatus - ultrastructure Hepatocytes HIDROLISIS HYDROLYSE Lactones - pharmacology MALADIE FONGIQUE Molecular and cellular biology Mycotoxins - pharmacology ORGANISMOS PATOGENOS PHYTOTOXICITE PHYTOTOXINE Plant cells Plant physiology and development Plant Proteins - metabolism Plants Polysaccharides Secretion Secretion. Exocytosis SINTOMAS STRUCTURE CELLULAIRE SYMPTOME Trees - drug effects Trees - ultrastructure ULTRAESTRUCTURA ULTRASTRUCTURE
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