Extracellular L‐arginine is required for optimal NO synthesis by eNOS and iNOS in the rat mesenteric artery wall

The formation of NO from endothelial nitric oxide synthase (eNOS) in rat superior mesenteric artery rings was dependent on extracellular L‐arginine, and was optimal at a concentration of L‐arginine close to the plasma level (carbachol‐stimulated NO: control 15.7±0.9, L‐arginine 100 μM 22.8±1.3 nM)....

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