The vascular activity of some isoflavone metabolites: implications for a cardioprotective role

Legume‐derived isoflavones such as genistein, diadzein and equol have been associated with a reduction in risk of cardiovascular disease. In the current study, we explore the vascular activity of several isoflavone metabolites namely dihydrodaidzein, cis and trans‐tetrahydrodaidzein and dehydroequol...

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Veröffentlicht in:	British journal of pharmacology 2001-06, Vol.133 (4), p.595-605
Hauptverfasser:	Chin‐Dusting, Jaye P F, Fisher, Lisa J, Lewis, Tamara V, Piekarska, Anna, Nestel, Paul J, Husband, Alan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals aorta Aorta - drug effects Aorta - physiology Biological and medical sciences Cardiovascular system endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Estradiol - pharmacology In Vitro Techniques Isoflavone metabolites Isoflavones - metabolism Isoflavones - pharmacology Lipoproteins, LDL - antagonists & inhibitors Male Medical sciences Miscellaneous Norepinephrine - pharmacology Pharmacology. Drug treatments Protective Agents - metabolism Protective Agents - pharmacology rat Rats Rats, Sprague-Dawley vascular Vasoconstriction - drug effects Vasoconstrictor Agents - pharmacology Vasodilation - drug effects Vasodilator Agents - pharmacology
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