Use of Monoclonal and Polyclonal Antibodies against DNA Adducts for the Detection of DNA Lesions in Isolated DNA and in Single Cells

Interaction of genotoxic chemicals with their intracellular target, i.e., DNA, may result in the formation of covalent adducts. Various methods have been developed to estimate exposure to genotoxic chemicals by means of molecular dosimetry of DNA adducts. Such experiments have generally been carried...

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